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Functional variation in allelic methylomes underscores a strong genetic contribution and reveals novel epigenetic alterations in the human epigenome.
Cheung WA, Shao X, Morin A, Siroux V, Kwan T, Ge B, Aïssi D, Chen L, Vasquez L, Allum F, Guénard F, Bouzigon E, Simon MM, Boulier E, Redensek A, Watt S, Datta A, Clarke L, Flicek P, Mead D, Paul DS, Beck S, Bourque G, Lathrop M, Tchernof A, Vohl MC, Demenais F, Pin I, Downes K, Stunnenberg HG, Soranzo N, Pastinen T, Grundberg E. Cheung WA, et al. Among authors: pin i. Genome Biol. 2017 Mar 10;18(1):50. doi: 10.1186/s13059-017-1173-7. Genome Biol. 2017. PMID: 28283040 Free PMC article.
Familial resemblance of asthma severity in the EGEA* study.
Pin I, Siroux V, Cans C, Kauffmann F, Maccario J, Pison C, Dizier MH. Pin I, et al. Am J Respir Crit Care Med. 2002 Jan 15;165(2):185-9. doi: 10.1164/ajrccm.165.2.2012019. Am J Respir Crit Care Med. 2002. PMID: 11790652
Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families.
Bouzigon E, Dizier MH, Krähenbühl C, Lemainque A, Annesi-Maesano I, Betard C, Bousquet J, Charpin D, Gormand F, Guilloud-Bataille M, Just J, Le Moual N, Maccario J, Matran R, Neukirch F, Oryszczyn MP, Paty E, Pin I, Rosenberg-Bourgin M, Vervloet D, Kauffmann F, Lathrop M, Demenais F. Bouzigon E, et al. Among authors: pin i. Hum Mol Genet. 2004 Dec 15;13(24):3103-13. doi: 10.1093/hmg/ddh340. Epub 2004 Oct 27. Hum Mol Genet. 2004. PMID: 15509591
Evidence for linkage of a new region (11p14) to eczema and allergic diseases.
Guilloud-Bataille M, Bouzigon E, Annesi-Maesano I, Bousquet J, Charpin D, Gormand F, Hochez J, Just J, Lemainque A, Le Moual N, Matran R, Neukirch F, Oryszczyn MP, Paty E, Pin I, Vervloet D, Kauffmann F, Lathrop M, Demenais F, Dizier MH. Guilloud-Bataille M, et al. Among authors: pin i. Hum Genet. 2008 Jan;122(6):605-14. doi: 10.1007/s00439-007-0439-7. Epub 2007 Oct 18. Hum Genet. 2008. PMID: 17943316 Free PMC article.
Replication of association between ADAM33 polymorphisms and psoriasis.
Siroux V, Bouzigon E, Dizier MH, Pin I, Demenais F, Kauffmann F; EGEA cooperative group. Siroux V, et al. Among authors: pin i. PLoS One. 2008 Jun 18;3(6):e2448. doi: 10.1371/journal.pone.0002448. PLoS One. 2008. PMID: 18560587 Free PMC article.
Effect of 17q21 variants and smoking exposure in early-onset asthma.
Bouzigon E, Corda E, Aschard H, Dizier MH, Boland A, Bousquet J, Chateigner N, Gormand F, Just J, Le Moual N, Scheinmann P, Siroux V, Vervloet D, Zelenika D, Pin I, Kauffmann F, Lathrop M, Demenais F. Bouzigon E, et al. Among authors: pin i. N Engl J Med. 2008 Nov 6;359(19):1985-94. doi: 10.1056/NEJMoa0806604. Epub 2008 Oct 15. N Engl J Med. 2008. PMID: 18923164 Free article.
CD14 and toll-like receptor gene polymorphisms, country living, and asthma in adults.
Smit LA, Siroux V, Bouzigon E, Oryszczyn MP, Lathrop M, Demenais F, Kauffmann F; Epidemiological Study on the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy (EGEA) Cooperative Group. Smit LA, et al. Am J Respir Crit Care Med. 2009 Mar 1;179(5):363-8. doi: 10.1164/rccm.200810-1533OC. Epub 2008 Dec 18. Am J Respir Crit Care Med. 2009. PMID: 19096003 Free article.
A large-scale, consortium-based genomewide association study of asthma.
Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM; GABRIEL Consortium. Moffatt MF, et al. N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312. N Engl J Med. 2010. PMID: 20860503 Free PMC article.
Mold allergen sensitization in adult asthma according to integrin β3 polymorphisms and Toll-like receptor 2/+596 genotype.
Smit LA, Bouzigon E, Bousquet J, Le Moual N, Nadif R, Pin I, Lathrop M, Demenais F, Kauffmann F, Siroux V; Epidemiological Study on the Genetics and Environment of Asthma. Smit LA, et al. Among authors: pin i. J Allergy Clin Immunol. 2011 Jul;128(1):185-191.e7. doi: 10.1016/j.jaci.2011.04.007. Epub 2011 May 13. J Allergy Clin Immunol. 2011. PMID: 21570717 Free article.
302 results