Tomlinson I - Search Results

1

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.

Shimelis H, Mesman RLS, Von Nicolai C, Ehlen A, Guidugli L, Martin C, Calléja FMGR, Meeks H, Hallberg E, Hinton J, Lilyquist J, Hu C, Aalfs CM, Aittomäki K, Andrulis I, Anton-Culver H, Arndt V, Beckmann MW, Benitez J, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Brauch H, Brennan P, Brenner H, Broeks A, Brouwers B, Brüning T, Burwinkel B, Chang-Claude J, Chenevix-Trench G, Cheng CY, Choi JY, Collée JM, Cox A, Cross SS, Czene K, Darabi H, Dennis J, Dörk T, Dos-Santos-Silva I, Dunning AM, Fasching PA, Figueroa J, Flyger H, García-Closas M, Giles GG, Glendon G, Guénel P, Haiman CA, Hall P, Hamann U, Hartman M, Hogervorst FB, Hollestelle A, Hopper JL, Ito H, Jakubowska A, Kang D, Kosma VM, Kristensen V, Lai KN, Lambrechts D, Marchand LL, Li J, Lindblom A, Lophatananon A, Lubinski J, Machackova E, Mannermaa A, Margolin S, Marme F, Matsuo K, Miao H, Michailidou K, Milne RL, Muir K, Neuhausen SL, Nevanlinna H, Olson JE, Olswold C, Oosterwijk JJC, Osorio A, Peterlongo P, Peto J, Pharoah PDP, Pylkäs K, Radice P, Rashid MU, Rhenius V, Rudolph A, Sangrajrang S, Sawyer EJ, Schmidt MK, Schoemaker MJ, Seynaeve C, Shah M, Shen CY, Shrubsole M, Shu XO, Slager S, Southey MC, Stram DO, Swe… See abstract for full author list ➔ Shimelis H, et al. Among authors: tomlinson i. Cancer Res. 2017 Jun 1;77(11):2789-2799. doi: 10.1158/0008-5472.CAN-16-2568. Epub 2017 Mar 10. Cancer Res. 2017. PMID: 28283652 Free PMC article.

2

Exclusion of PTEN and 10q22-24 as the susceptibility locus for juvenile polyposis syndrome.

Marsh DJ, Roth S, Lunetta KL, Hemminki A, Dahia PL, Sistonen P, Zheng Z, Caron S, van Orsouw NJ, Bodmer WF, Cottrell SE, Dunlop MG, Eccles D, Hodgson SV, Järvinen H, Kellokumpu I, Markie D, Neale K, Phillips R, Rozen P, Syngal S, Vijg J, Tomlinson IP, Aaltonen LA, Eng C. Marsh DJ, et al. Among authors: tomlinson ip. Cancer Res. 1997 Nov 15;57(22):5017-21. Cancer Res. 1997. PMID: 9371495

3

Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.

Sawyer EJ, Hanby AM, Ellis P, Lakhani SR, Ellis IO, Boyle S, Tomlinson IP. Sawyer EJ, et al. Among authors: tomlinson ip. Am J Pathol. 2000 Mar;156(3):1093-8. doi: 10.1016/S0002-9440(10)64977-2. Am J Pathol. 2000. PMID: 10702425 Free PMC article.

4

Mutations in normal breast tissue and breast tumours.

Tomlinson IP. Tomlinson IP. Breast Cancer Res. 2001;3(5):299-303. doi: 10.1186/bcr311. Epub 2001 Jul 26. Breast Cancer Res. 2001. PMID: 11597318 Free PMC article. Review.

5

Malignant phyllodes tumours show stromal overexpression of c-myc and c-kit.

Sawyer EJ, Poulsom R, Hunt FT, Jeffery R, Elia G, Ellis IO, Ellis P, Tomlinson IP, Hanby AM. Sawyer EJ, et al. J Pathol. 2003 May;200(1):59-64. doi: 10.1002/path.1318. J Pathol. 2003. PMID: 12692842

6

Beta-catenin abnormalities and associated insulin-like growth factor overexpression are important in phyllodes tumours and fibroadenomas of the breast.

Sawyer EJ, Hanby AM, Poulsom R, Jeffery R, Gillett CE, Ellis IO, Ellis P, Tomlinson IP. Sawyer EJ, et al. J Pathol. 2003 Aug;200(5):627-32. doi: 10.1002/path.1391. J Pathol. 2003. PMID: 12898599

7

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.

Sieber OM, Howarth KM, Thirlwell C, Rowan A, Mandir N, Goodlad RA, Gilkar A, Spencer-Dene B, Stamp G, Johnson V, Silver A, Yang H, Miller JH, Ilyas M, Tomlinson IP. Sieber OM, et al. Cancer Res. 2004 Dec 15;64(24):8876-81. doi: 10.1158/0008-5472.CAN-04-2958. Cancer Res. 2004. PMID: 15604247

8

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.

Halford S, Rowan A, Sawyer E, Talbot I, Tomlinson I. Halford S, et al. Among authors: tomlinson i. Gut. 2005 Jun;54(6):797-802. doi: 10.1136/gut.2004.059535. Gut. 2005. PMID: 15888787 Free PMC article.

9

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.

Kemp Z, Rowan A, Chambers W, Wortham N, Halford S, Sieber O, Mortensen N, von Herbay A, Gunther T, Ilyas M, Tomlinson I. Kemp Z, et al. Among authors: tomlinson i. Cancer Res. 2005 Dec 15;65(24):11361-6. doi: 10.1158/0008-5472.CAN-05-2565. Cancer Res. 2005. PMID: 16357143

10

Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom.

Kemp ZE, Carvajal-Carmona LG, Barclay E, Gorman M, Martin L, Wood W, Rowan A, Donohue C, Spain S, Jaeger E, Evans DG, Maher ER, Bishop T, Thomas H, Houlston R, Tomlinson I; Colorectal Tumour Gene Identification Study Consortium. Kemp ZE, et al. Among authors: tomlinson i. Cancer Res. 2006 May 15;66(10):5003-6. doi: 10.1158/0008-5472.CAN-05-4074. Cancer Res. 2006. PMID: 16707420

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