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The redox environment triggers conformational changes and aggregation of hIAPP in Type II Diabetes.
Rodriguez Camargo DC, Tripsianes K, Buday K, Franko A, Göbl C, Hartlmüller C, Sarkar R, Aichler M, Mettenleiter G, Schulz M, Böddrich A, Erck C, Martens H, Walch AK, Madl T, Wanker EE, Conrad M, de Angelis MH, Reif B. Rodriguez Camargo DC, et al. Among authors: aichler m. Sci Rep. 2017 Mar 13;7:44041. doi: 10.1038/srep44041. Sci Rep. 2017. PMID: 28287098 Free PMC article.
Epigallocatechin gallate (EGCG) reduces the intensity of pancreatic amyloid fibrils in human islet amyloid polypeptide (hIAPP) transgenic mice.
Franko A, Rodriguez Camargo DC, Böddrich A, Garg D, Rodriguez Camargo A, Rathkolb B, Janik D, Aichler M, Feuchtinger A, Neff F, Fuchs H, Wanker EE, Reif B, Häring HU, Peter A, Hrabě de Angelis M. Franko A, et al. Among authors: aichler m. Sci Rep. 2018 Jan 18;8(1):1116. doi: 10.1038/s41598-017-18807-8. Sci Rep. 2018. PMID: 29348618 Free PMC article.
hIAPP forms toxic oligomers in plasma.
Rodriguez Camargo DC , Garg D , Buday K , Franko A , Rodriguez Camargo A , Schmidt F , Cox SJ , Suladze S , Haslbeck M , Mideksa YG , Gemmecker G , Aichler M , Mettenleiter G , Schulz M , Walch AK , Hrabě de Angelis M , Feige MJ , Sierra CA , Conrad M , Tripsianes K , Ramamoorthy A , Reif B . Rodriguez Camargo DC , et al. Among authors: aichler m. Chem Commun (Camb). 2018 May 24;54(43):5426-5429. doi: 10.1039/c8cc03097a. Chem Commun (Camb). 2018. PMID: 29745410 Free PMC article.
Efficient isolation of pure and functional mitochondria from mouse tissues using automated tissue disruption and enrichment with anti-TOM22 magnetic beads.
Franko A, Baris OR, Bergschneider E, von Toerne C, Hauck SM, Aichler M, Walch AK, Wurst W, Wiesner RJ, Johnston IC, de Angelis MH. Franko A, et al. Among authors: aichler m. PLoS One. 2013 Dec 12;8(12):e82392. doi: 10.1371/journal.pone.0082392. eCollection 2013. PLoS One. 2013. PMID: 24349272 Free PMC article.
Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility.
Ingold I, Aichler M, Yefremova E, Roveri A, Buday K, Doll S, Tasdemir A, Hoffard N, Wurst W, Walch A, Ursini F, Friedmann Angeli JP, Conrad M. Ingold I, et al. Among authors: aichler m. J Biol Chem. 2015 Jun 5;290(23):14668-78. doi: 10.1074/jbc.M115.656363. Epub 2015 Apr 28. J Biol Chem. 2015. PMID: 25922076 Free PMC article.
109 results