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TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway.
Moujalled D, Grubman A, Acevedo K, Yang S, Ke YD, Moujalled DM, Duncan C, Caragounis A, Perera ND, Turner BJ, Prudencio M, Petrucelli L, Blair I, Ittner LM, Crouch PJ, Liddell JR, White AR. Moujalled D, et al. Among authors: grubman a. Hum Mol Genet. 2017 May 1;26(9):1732-1746. doi: 10.1093/hmg/ddx093. Hum Mol Genet. 2017. PMID: 28334913
Increased zinc and manganese in parallel with neurodegeneration, synaptic protein changes and activation of Akt/GSK3 signaling in ovine CLN6 neuronal ceroid lipofuscinosis.
Kanninen KM, Grubman A, Meyerowitz J, Duncan C, Tan JL, Parker SJ, Crouch PJ, Paterson BM, Hickey JL, Donnelly PS, Volitakis I, Tammen I, Palmer DN, White AR. Kanninen KM, et al. Among authors: grubman a. PLoS One. 2013;8(3):e58644. doi: 10.1371/journal.pone.0058644. Epub 2013 Mar 14. PLoS One. 2013. PMID: 23516525 Free PMC article.
Copper modulates the large dense core vesicle secretory pathway in PC12 cells.
Duncan C, Bica L, Crouch PJ, Caragounis A, Lidgerwood GE, Parker SJ, Meyerowitz J, Volitakis I, Liddell JR, Raghupathi R, Paterson BM, Duffield MD, Cappai R, Donnelly PS, Grubman A, Camakaris J, Keating DJ, White AR. Duncan C, et al. Among authors: grubman a. Metallomics. 2013 Jun;5(6):700-14. doi: 10.1039/c3mt20231c. Metallomics. 2013. PMID: 23661118
Kinase Inhibitor Screening Identifies Cyclin-Dependent Kinases and Glycogen Synthase Kinase 3 as Potential Modulators of TDP-43 Cytosolic Accumulation during Cell Stress.
Moujalled D, James JL, Parker SJ, Lidgerwood GE, Duncan C, Meyerowitz J, Nonaka T, Hasegawa M, Kanninen KM, Grubman A, Liddell JR, Crouch PJ, White AR. Moujalled D, et al. Among authors: grubman a. PLoS One. 2013 Jun 26;8(6):e67433. doi: 10.1371/journal.pone.0067433. Print 2013. PLoS One. 2013. PMID: 23840699 Free PMC article.
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry.
Hare DJ, Grubman A, Ryan TM, Lothian A, Liddell JR, Grimm R, Matsuda T, Doble PA, Cherny RA, Bush AI, White AR, Masters CL, Roberts BR. Hare DJ, et al. Among authors: grubman a. Metallomics. 2013 Dec;5(12):1656-62. doi: 10.1039/c3mt00227f. Epub 2013 Oct 17. Metallomics. 2013. PMID: 24132241
Neuroinflammation and copper in Alzheimer's disease.
Choo XY, Alukaidey L, White AR, Grubman A. Choo XY, et al. Among authors: grubman a. Int J Alzheimers Dis. 2013;2013:145345. doi: 10.1155/2013/145345. Epub 2013 Nov 28. Int J Alzheimers Dis. 2013. PMID: 24369524 Free PMC article. Review.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM. Grubman A, et al. Acta Neuropathol Commun. 2014 Feb 28;2:25. doi: 10.1186/2051-5960-2-25. Acta Neuropathol Commun. 2014. PMID: 24581221 Free PMC article.
43 results