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A role for noncoding variation in schizophrenia.
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P. Roussos P, et al. Among authors: voloudakis g. Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016/j.celrep.2014.10.015. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453756 Free PMC article.
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia.
Moreno JL, Miranda-Azpiazu P, García-Bea A, Younkin J, Cui M, Kozlenkov A, Ben-Ezra A, Voloudakis G, Fakira AK, Baki L, Ge Y, Georgakopoulos A, Morón JA, Milligan G, López-Giménez JF, Robakis NK, Logothetis DE, Meana JJ, González-Maeso J. Moreno JL, et al. Among authors: voloudakis g. Sci Signal. 2016 Jan 12;9(410):ra5. doi: 10.1126/scisignal.aab0467. Sci Signal. 2016. PMID: 26758213 Free PMC article.
Presenilin1/γ-secretase protects neurons from glucose deprivation-induced death by regulating miR-212 and PEA15.
Huang Q, Voloudakis G, Ren Y, Yoon Y, Zhang E, Kajiwara Y, Shao Z, Xuan Z, Lebedev D, Georgakopoulos A, Robakis NK. Huang Q, et al. Among authors: voloudakis g. FASEB J. 2018 Jan;32(1):243-253. doi: 10.1096/fj.201700447RR. Epub 2017 Aug 30. FASEB J. 2018. PMID: 28855274 Free PMC article.
These observations have implications for mechanisms of neuronal death under conditions of reduced glucose and may provide targets for intervention in neurodegenerative disorders.-Huang, Q., Voloudakis, G., Ren, Y., Yoon, Y., Zhang, E., Kajiwara, Y., Shao, Z., Xuan, …
These observations have implications for mechanisms of neuronal death under conditions of reduced glucose and may provide targets for interv …
Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci.
Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Fullard JF, et al. Among authors: voloudakis g. Hum Mol Genet. 2018 Jun 29;29(16):2812. doi: 10.1093/hmg/ddy229. Online ahead of print. Hum Mol Genet. 2018. PMID: 29982455 Free PMC article. No abstract available.
CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder.
Hoffman GE, Bendl J, Voloudakis G, Montgomery KS, Sloofman L, Wang YC, Shah HR, Hauberg ME, Johnson JS, Girdhar K, Song L, Fullard JF, Kramer R, Hahn CG, Gur R, Marenco S, Lipska BK, Lewis DA, Haroutunian V, Hemby S, Sullivan P, Akbarian S, Chess A, Buxbaum JD, Crawford GE, Domenici E, Devlin B, Sieberts SK, Peters MA, Roussos P. Hoffman GE, et al. Among authors: voloudakis g. Sci Data. 2019 Sep 24;6(1):180. doi: 10.1038/s41597-019-0183-6. Sci Data. 2019. PMID: 31551426 Free PMC article.
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