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Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ. Baar MP, et al. Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031. Cell. 2017. PMID: 28340339 Free PMC article.
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling.
Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, Brenkman AB, Campisi J, Burgering BM, Hoeijmakers JH, de Keizer PL. Kruiswijk F, et al. Among authors: baar mp. Oncogene. 2016 Apr 28;35(17):2166-77. doi: 10.1038/onc.2015.282. Epub 2015 Aug 17. Oncogene. 2016. PMID: 26279295 Free PMC article.
Maintenance and repair of an aging life cycle.
Baar MP, Van Willigenburg H, de Keizer PLJ. Baar MP, et al. Oncotarget. 2017 May 21;8(50):86985-86986. doi: 10.18632/oncotarget.18046. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152057 Free PMC article. No abstract available.
Senescent Cells Drive Frailty through Systemic Signals.
Lehmann J, Baar MP, de Keizer PLJ. Lehmann J, et al. Among authors: baar mp. Trends Mol Med. 2018 Nov;24(11):917-918. doi: 10.1016/j.molmed.2018.09.003. Epub 2018 Oct 3. Trends Mol Med. 2018. PMID: 30292430
Different responses to DNA damage determine ageing differences between organs.
Vougioukalaki M, Demmers J, Vermeij WP, Baar M, Bruens S, Magaraki A, Kuijk E, Jager M, Merzouk S, Brandt RMC, Kouwenberg J, van Boxtel R, Cuppen E, Pothof J, Hoeijmakers JHJ. Vougioukalaki M, et al. Aging Cell. 2022 Apr;21(4):e13562. doi: 10.1111/acel.13562. Epub 2022 Mar 4. Aging Cell. 2022. PMID: 35246937 Free PMC article.
Genome-wide RNA polymerase stalling shapes the transcriptome during aging.
Gyenis A, Chang J, Demmers JJPG, Bruens ST, Barnhoorn S, Brandt RMC, Baar MP, Raseta M, Derks KWJ, Hoeijmakers JHJ, Pothof J. Gyenis A, et al. Among authors: baar mp. Nat Genet. 2023 Feb;55(2):268-279. doi: 10.1038/s41588-022-01279-6. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36658433 Free PMC article.
Whole-genome copy-number analysis identifies new leads for chromosomal aberrations involved in the oncogenesis and metastastic behavior of uveal melanomas.
van Engen-van Grunsven AC, Baar MP, Pfundt R, Rijntjes J, Küsters-Vandevelde HV, Delbecq AL, Keunen JE, Klevering JB, Wesseling P, Blokx WA, Groenen PJ. van Engen-van Grunsven AC, et al. Among authors: baar mp. Melanoma Res. 2015 Jun;25(3):200-9. doi: 10.1097/CMR.0000000000000152. Melanoma Res. 2015. PMID: 25756553
26 results