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Transaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.
Bennett CF, Kwon JJ, Chen C, Russell J, Acosta K, Burnaevskiy N, Crane MM, Bitto A, Vander Wende H, Simko M, Pineda V, Rossner R, Wasko BM, Choi H, Chen S, Park S, Jafari G, Sands B, Perez Olsen C, Mendenhall AR, Morgan PG, Kaeberlein M. Bennett CF, et al. Among authors: choi h. PLoS Genet. 2017 Mar 29;13(3):e1006695. doi: 10.1371/journal.pgen.1006695. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28355222 Free PMC article.
DDS promotes longevity through a microbiome-mediated starvation signal.
Choi H, Cho SC, Ha YW, Ocampo B, Park S, Chen S, Bennett CF, Han J, Rossner R, Kang JS, Lee YL, Park SC, Kaeberlein M. Choi H, et al. Transl Med Aging. 2019;3:64-69. doi: 10.1016/j.tma.2019.07.001. Epub 2019 Jul 3. Transl Med Aging. 2019. PMID: 32190786 Free PMC article.
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