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Clumping Factor B Promotes Adherence of Staphylococcus aureus to Corneocytes in Atopic Dermatitis.
Fleury OM, McAleer MA, Feuillie C, Formosa-Dague C, Sansevere E, Bennett DE, Towell AM, McLean WHI, Kezic S, Robinson DA, Fallon PG, Foster TJ, Dufrêne YF, Irvine AD, Geoghegan JA. Fleury OM, et al. Among authors: fallon pg. Infect Immun. 2017 May 23;85(6):e00994-16. doi: 10.1128/IAI.00994-16. Print 2017 Jun. Infect Immun. 2017. PMID: 28373353 Free PMC article.
Filaggrin loss-of-function mutations are associated with enhanced expression of IL-1 cytokines in the stratum corneum of patients with atopic dermatitis and in a murine model of filaggrin deficiency.
Kezic S, O'Regan GM, Lutter R, Jakasa I, Koster ES, Saunders S, Caspers P, Kemperman PM, Puppels GJ, Sandilands A, Chen H, Campbell LE, Kroboth K, Watson R, Fallon PG, McLean WH, Irvine AD. Kezic S, et al. Among authors: fallon pg. J Allergy Clin Immunol. 2012 Apr;129(4):1031-9.e1. doi: 10.1016/j.jaci.2011.12.989. Epub 2012 Feb 8. J Allergy Clin Immunol. 2012. PMID: 22322004 Free PMC article.
Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects.
Saunders SP, Goh CS, Brown SJ, Palmer CN, Porter RM, Cole C, Campbell LE, Gierlinski M, Barton GJ, Schneider G, Balmain A, Prescott AR, Weidinger S, Baurecht H, Kabesch M, Gieger C, Lee YA, Tavendale R, Mukhopadhyay S, Turner SW, Madhok VB, Sullivan FM, Relton C, Burn J, Meggitt S, Smith CH, Allen MA, Barker JN, Reynolds NJ, Cordell HJ, Irvine AD, McLean WH, Sandilands A, Fallon PG. Saunders SP, et al. Among authors: fallon pg. J Allergy Clin Immunol. 2013 Nov;132(5):1121-9. doi: 10.1016/j.jaci.2013.08.046. Epub 2013 Sep 29. J Allergy Clin Immunol. 2013. PMID: 24084074 Free PMC article.
Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.
Saunders SP, Moran T, Floudas A, Wurlod F, Kaszlikowska A, Salimi M, Quinn EM, Oliphant CJ, Núñez G, McManus R, Hams E, Irvine AD, McKenzie AN, Ogg GS, Fallon PG. Saunders SP, et al. Among authors: fallon pg. J Allergy Clin Immunol. 2016 Feb;137(2):482-91. doi: 10.1016/j.jaci.2015.06.045. Epub 2015 Aug 20. J Allergy Clin Immunol. 2016. PMID: 26299987 Free PMC article.
Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year.
Kennedy EA, Connolly J, Hourihane JO, Fallon PG, McLean WHI, Murray D, Jo JH, Segre JA, Kong HH, Irvine AD. Kennedy EA, et al. Among authors: fallon pg. J Allergy Clin Immunol. 2017 Jan;139(1):166-172. doi: 10.1016/j.jaci.2016.07.029. Epub 2016 Sep 5. J Allergy Clin Immunol. 2017. PMID: 27609659 Free PMC article.
297 results