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Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression.
Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Olié E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, Åslund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munafò MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx BWJH, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, Völzke H, Weinstein M, Whooley M, Nurnberger JI Jr, Breslau N, Bierut LJ. Culverhouse RC, et al. Among authors: lajnef m. Mol Psychiatry. 2018 Jan;23(1):133-142. doi: 10.1038/mp.2017.44. Epub 2017 Apr 4. Mol Psychiatry. 2018. PMID: 28373689 Free PMC article.
Clinical expression of bipolar disorder type I as a function of age and polarity at onset: convergent findings in samples from France and the United States.
Etain B, Lajnef M, Bellivier F, Mathieu F, Raust A, Cochet B, Gard S, M'Bailara K, Kahn JP, Elgrabli O, Cohen R, Jamain S, Vieta E, Leboyer M, Henry C. Etain B, et al. Among authors: lajnef m, m bailara k. J Clin Psychiatry. 2012 Apr;73(4):e561-6. doi: 10.4088/JCP.10m06504. J Clin Psychiatry. 2012. PMID: 22579163 Free article.
Genetic heterogeneity according to age at onset in bipolar disorder: a combined positional cloning and candidate gene approach.
Dizier MH, Etain B, Lajnef M, Lathrop M, Grozeva D, Craddock N, Henry C, Gard S, Jamain S, Leboyer M, Bellivier F, Mathieu F. Dizier MH, et al. Among authors: lajnef m. Am J Med Genet B Neuropsychiatr Genet. 2012 Sep;159B(6):653-9. doi: 10.1002/ajmg.b.32069. Epub 2012 May 24. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22628130
Duration of untreated bipolar disorder: missed opportunities on the long road to optimal treatment.
Drancourt N, Etain B, Lajnef M, Henry C, Raust A, Cochet B, Mathieu F, Gard S, Mbailara K, Zanouy L, Kahn JP, Cohen RF, Wajsbrot-Elgrabli O, Leboyer M, Scott J, Bellivier F. Drancourt N, et al. Among authors: lajnef m. Acta Psychiatr Scand. 2013 Feb;127(2):136-44. doi: 10.1111/j.1600-0447.2012.01917.x. Epub 2012 Aug 20. Acta Psychiatr Scand. 2013. PMID: 22901015
The HLA-G low expressor genotype is associated with protection against bipolar disorder.
Debnath M, Busson M, Jamain S, Etain B, Hamdani N, Oliveira J, Boukouaci W, Amokrane K, Moins-Teisserenc H, Lajnef M, Bengoufa D, Malafosse A, Bellivier F, Henry C, Kahn JP, Krishnamoorthy R, Charron D, Leboyer M, Tamouza R. Debnath M, et al. Among authors: lajnef m. Hum Immunol. 2013 May;74(5):593-7. doi: 10.1016/j.humimm.2012.11.032. Epub 2012 Dec 12. Hum Immunol. 2013. PMID: 23246584 Free article.
Chronotypes of bipolar patients in remission: validation of the French version of the circadian type inventory in the FACE-BD sample.
Boudebesse C, Lajnef M, Geoffroy PA, Bellivier F, Nieto I, Gard S, Olié E, Azorin JM, Kahn JP, Bougerol T, Passerieux C, Aubin V, Milhiet V, Folkard S; French Academic Centres of Expertise for Bipolar Disorders (FACE-BD) Collaborators; Leboyer M, Henry C, Etain B. Boudebesse C, et al. Among authors: lajnef m. Chronobiol Int. 2013 Oct;30(8):1042-9. doi: 10.3109/07420528.2013.798330. Epub 2013 Jul 18. Chronobiol Int. 2013. PMID: 23866053
Association between circadian genes, bipolar disorders and chronotypes.
Etain B, Jamain S, Milhiet V, Lajnef M, Boudebesse C, Dumaine A, Mathieu F, Gombert A, Ledudal K, Gard S, Kahn JP, Henry C, Boland A, Zelenika D, Lechner D, Lathrop M, Leboyer M, Bellivier F. Etain B, et al. Among authors: lajnef m. Chronobiol Int. 2014 Aug;31(7):807-14. doi: 10.3109/07420528.2014.906445. Epub 2014 Apr 9. Chronobiol Int. 2014. PMID: 24716566
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