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Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression.
Culverhouse RC, Saccone NL, Horton AC, Ma Y, Anstey KJ, Banaschewski T, Burmeister M, Cohen-Woods S, Etain B, Fisher HL, Goldman N, Guillaume S, Horwood J, Juhasz G, Lester KJ, Mandelli L, Middeldorp CM, Olié E, Villafuerte S, Air TM, Araya R, Bowes L, Burns R, Byrne EM, Coffey C, Coventry WL, Gawronski KAB, Glei D, Hatzimanolis A, Hottenga JJ, Jaussent I, Jawahar C, Jennen-Steinmetz C, Kramer JR, Lajnef M, Little K, Zu Schwabedissen HM, Nauck M, Nederhof E, Petschner P, Peyrot WJ, Schwahn C, Sinnamon G, Stacey D, Tian Y, Toben C, Van der Auwera S, Wainwright N, Wang JC, Willemsen G, Anderson IM, Arolt V, Åslund C, Bagdy G, Baune BT, Bellivier F, Boomsma DI, Courtet P, Dannlowski U, de Geus EJC, Deakin JFW, Easteal S, Eley T, Fergusson DM, Goate AM, Gonda X, Grabe HJ, Holzman C, Johnson EO, Kennedy M, Laucht M, Martin NG, Munafò MR, Nilsson KW, Oldehinkel AJ, Olsson CA, Ormel J, Otte C, Patton GC, Penninx BWJH, Ritchie K, Sarchiapone M, Scheid JM, Serretti A, Smit JH, Stefanis NC, Surtees PG, Völzke H, Weinstein M, Whooley M, Nurnberger JI Jr, Breslau N, Bierut LJ. Culverhouse RC, et al. Among authors: toben c. Mol Psychiatry. 2018 Jan;23(1):133-142. doi: 10.1038/mp.2017.44. Epub 2017 Apr 4. Mol Psychiatry. 2018. PMID: 28373689 Free PMC article.
Co-expression network analysis of peripheral blood transcriptome identifies dysregulated protein processing in endoplasmic reticulum and immune response in recurrent MDD in older adults.
Ciobanu LG, Sachdev PS, Trollor JN, Reppermund S, Thalamuthu A, Mather KA, Cohen-Woods S, Stacey D, Toben C, Schubert KO, Baune BT. Ciobanu LG, et al. Among authors: toben c. J Psychiatr Res. 2018 Dec;107:19-27. doi: 10.1016/j.jpsychires.2018.09.017. Epub 2018 Oct 1. J Psychiatr Res. 2018. PMID: 30312913
Large-scale evidence for an association between low-grade peripheral inflammation and brain structural alterations in major depression in the BiDirect study.
Opel N, Cearns M, Clark S, Toben C, Grotegerd D, Heindel W, Kugel H, Teuber A, Minnerup H, Berger K, Dannlowski U, Baune BT. Opel N, et al. Among authors: toben c. J Psychiatry Neurosci. 2019 Nov 1;44(6):423-431. doi: 10.1503/jpn.180208. J Psychiatry Neurosci. 2019. PMID: 31304733 Free PMC article.
Short-term environmental enrichment, and not physical exercise, alleviate cognitive decline and anxiety from middle age onwards without affecting hippocampal gene expression.
Singhal G, Morgan J, Jawahar MC, Corrigan F, Jaehne EJ, Toben C, Breen J, Pederson SM, Hannan AJ, Baune BT. Singhal G, et al. Among authors: toben c. Cogn Affect Behav Neurosci. 2019 Oct;19(5):1143-1169. doi: 10.3758/s13415-019-00743-x. Cogn Affect Behav Neurosci. 2019. PMID: 31463713
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