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Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO).
Yu AM, Ingelman-Sundberg M, Cherrington NJ, Aleksunes LM, Zanger UM, Xie W, Jeong H, Morgan ET, Turnbaugh PJ, Klaassen CD, Bhatt AP, Redinbo MR, Hao P, Waxman DJ, Wang L, Zhong XB. Yu AM, et al. Among authors: zhong xb. Acta Pharm Sin B. 2017 Mar;7(2):241-248. doi: 10.1016/j.apsb.2016.12.006. Epub 2017 Feb 1. Acta Pharm Sin B. 2017. PMID: 28388695 Free PMC article.
Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver.
Li Y, Buckley D, Wang S, Klaassen CD, Zhong XB. Li Y, et al. Among authors: zhong xb. Drug Metab Dispos. 2009 Sep;37(9):1978-86. doi: 10.1124/dmd.109.027409. Epub 2009 Jun 18. Drug Metab Dispos. 2009. PMID: 19541828 Free PMC article.
Bile acids via FXR initiate the expression of major transporters involved in the enterohepatic circulation of bile acids in newborn mice.
Cui JY, Aleksunes LM, Tanaka Y, Fu ZD, Guo Y, Guo GL, Lu H, Zhong XB, Klaassen CD. Cui JY, et al. Among authors: zhong xb. Am J Physiol Gastrointest Liver Physiol. 2012 May 1;302(9):G979-96. doi: 10.1152/ajpgi.00370.2011. Epub 2012 Jan 19. Am J Physiol Gastrointest Liver Physiol. 2012. PMID: 22268101 Free PMC article.
124 results