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MDR1 deficiency impairs mitochondrial homeostasis and promotes intestinal inflammation.
Ho GT, Aird RE, Liu B, Boyapati RK, Kennedy NA, Dorward DA, Noble CL, Shimizu T, Carter RN, Chew ETS, Morton NM, Rossi AG, Sartor RB, Iredale JP, Satsangi J. Ho GT, et al. Among authors: iredale jp. Mucosal Immunol. 2018 Jan;11(1):120-130. doi: 10.1038/mi.2017.31. Epub 2017 Apr 12. Mucosal Immunol. 2018. PMID: 28401939 Free PMC article.
Metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency: implications for the pathogenesis of steatohepatitis.
Macfarlane DP, Zou X, Andrew R, Morton NM, Livingstone DE, Aucott RL, Nyirenda MJ, Iredale JP, Walker BR. Macfarlane DP, et al. Among authors: iredale jp. Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E402-9. doi: 10.1152/ajpendo.00331.2010. Epub 2010 Nov 30. Am J Physiol Endocrinol Metab. 2011. PMID: 21119028 Free PMC article.
Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells.
Crittenden S, Goepp M, Pollock J, Robb CT, Smyth DJ, Zhou Y, Andrews R, Tyrrell V, Gkikas K, Adima A, O'Connor RA, Davies L, Li XF, Yao HX, Ho GT, Zheng X, Mair A, Vermeren S, Qian BZ, Mole DJ, Gerasimidis K, Schwarze JKJ, Breyer RM, Arends MJ, O'Donnell VB, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Rossi AG, Howie SE, Yao C. Crittenden S, et al. Among authors: iredale jp. Sci Adv. 2021 Feb 12;7(7):eabd7954. doi: 10.1126/sciadv.abd7954. Print 2021 Feb. Sci Adv. 2021. PMID: 33579710 Free PMC article.
Increased angiogenesis protects against adipose hypoxia and fibrosis in metabolic disease-resistant 11β-hydroxysteroid dehydrogenase type 1 (HSD1)-deficient mice.
Michailidou Z, Turban S, Miller E, Zou X, Schrader J, Ratcliffe PJ, Hadoke PW, Walker BR, Iredale JP, Morton NM, Seckl JR. Michailidou Z, et al. Among authors: iredale jp. J Biol Chem. 2012 Feb 3;287(6):4188-97. doi: 10.1074/jbc.M111.259325. Epub 2011 Dec 12. J Biol Chem. 2012. PMID: 22158867 Free PMC article.
Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.
Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, Mole DJ, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Ghazal P, Howie SE, Rossi AG, Yao C. Duffin R, et al. Among authors: iredale jp. Science. 2016 Mar 18;351(6279):1333-8. doi: 10.1126/science.aad9903. Science. 2016. PMID: 26989254 Free PMC article.
11Beta-hydroxysteroid dehydrogenase-1 deficiency or inhibition enhances hepatic myofibroblast activation in murine liver fibrosis.
Zou X, Ramachandran P, Kendall TJ, Pellicoro A, Dora E, Aucott RL, Manwani K, Man TY, Chapman KE, Henderson NC, Forbes SJ, Webster SP, Iredale JP, Walker BR, Michailidou Z. Zou X, et al. Among authors: iredale jp. Hepatology. 2018 Jun;67(6):2167-2181. doi: 10.1002/hep.29734. Epub 2018 Feb 22. Hepatology. 2018. PMID: 29251794 Free PMC article.
Hepatic endoderm differentiation from human embryonic stem cells.
Hannoun Z, Filippi C, Sullivan G, Hay DC, Iredale JP. Hannoun Z, et al. Among authors: iredale jp. Curr Stem Cell Res Ther. 2010 Sep;5(3):233-44. doi: 10.2174/157488810791824403. Curr Stem Cell Res Ther. 2010. PMID: 20214561 Review.
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury.
Campana L, Starkey Lewis PJ, Pellicoro A, Aucott RL, Man J, O'Duibhir E, Mok SE, Ferreira-Gonzalez S, Livingstone E, Greenhalgh SN, Hull KL, Kendall TJ, Vernimmen D, Henderson NC, Boulter L, Gregory CD, Feng Y, Anderton SM, Forbes SJ, Iredale JP. Campana L, et al. Among authors: iredale jp. J Immunol. 2018 Feb 1;200(3):1169-1187. doi: 10.4049/jimmunol.1701247. Epub 2017 Dec 20. J Immunol. 2018. PMID: 29263216 Free PMC article.
177 results