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Fine-mapping of lipid regions in global populations discovers ethnic-specific signals and refines previously identified lipid loci.
Zubair N, Graff M, Luis Ambite J, Bush WS, Kichaev G, Lu Y, Manichaikul A, Sheu WH, Absher D, Assimes TL, Bielinski SJ, Bottinger EP, Buzkova P, Chuang LM, Chung RH, Cochran B, Dumitrescu L, Gottesman O, Haessler JW, Haiman C, Heiss G, Hsiung CA, Hung YJ, Hwu CM, Juang JJ, Le Marchand L, Lee IT, Lee WJ, Lin LA, Lin D, Lin SY, Mackey RH, Martin LW, Pasaniuc B, Peters U, Predazzi I, Quertermous T, Reiner AP, Robinson J, Rotter JI, Ryckman KK, Schreiner PJ, Stahl E, Tao R, Tsai MY, Waite LL, Wang TD, Buyske S, Ida Chen YD, Cheng I, Crawford DC, Loos RJF, Rich SS, Fornage M, North KE, Kooperberg C, Carty CL. Zubair N, et al. Among authors: dumitrescu l. Hum Mol Genet. 2016 Dec 15;25(24):5500-5512. doi: 10.1093/hmg/ddw358. Hum Mol Genet. 2016. PMID: 28426890 Free PMC article.
TREM2 gene expression associations with Alzheimer's disease neuropathology are region-specific: implications for cortical versus subcortical microglia.
Winfree RL, Seto M, Dumitrescu L, Menon V, De Jager P, Wang Y, Schneider J, Bennett DA, Jefferson AL, Hohman TJ. Winfree RL, et al. Among authors: dumitrescu l. Acta Neuropathol. 2023 Jun;145(6):733-747. doi: 10.1007/s00401-023-02564-2. Epub 2023 Mar 25. Acta Neuropathol. 2023. PMID: 36966244 Free PMC article.
Whole blood transcript and protein abundance of the vascular endothelial growth factor family relate to cognitive performance.
Libby JB, Seto M, Khan OA, Liu D, Petyuk V, Oliver NC, Choi MJ, Whitaker M, Patterson KL, Arul AB, Gifford KA, Blennow K, Zetterberg H, Dumitrescu L, Robinson RA, Jefferson AL, Hohman TJ. Libby JB, et al. Among authors: dumitrescu l. Neurobiol Aging. 2023 Apr;124:11-17. doi: 10.1016/j.neurobiolaging.2023.01.002. Epub 2023 Jan 7. Neurobiol Aging. 2023. PMID: 36680854 Free PMC article.
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
Dumitrescu L, Carty CL, Taylor K, Schumacher FR, Hindorff LA, Ambite JL, Anderson G, Best LG, Brown-Gentry K, Bůžková P, Carlson CS, Cochran B, Cole SA, Devereux RB, Duggan D, Eaton CB, Fornage M, Franceschini N, Haessler J, Howard BV, Johnson KC, Laston S, Kolonel LN, Lee ET, MacCluer JW, Manolio TA, Pendergrass SA, Quibrera M, Shohet RV, Wilkens LR, Haiman CA, Le Marchand L, Buyske S, Kooperberg C, North KE, Crawford DC. Dumitrescu L, et al. PLoS Genet. 2011 Jun;7(6):e1002138. doi: 10.1371/journal.pgen.1002138. Epub 2011 Jun 30. PLoS Genet. 2011. PMID: 21738485 Free PMC article.
Evidence for age as a modifier of genetic associations for lipid levels.
Dumitrescu L, Brown-Gentry K, Goodloe R, Glenn K, Yang W, Kornegay N, Pui CH, Relling MV, Crawford DC. Dumitrescu L, et al. Ann Hum Genet. 2011 Sep;75(5):589-97. doi: 10.1111/j.1469-1809.2011.00664.x. Epub 2011 Jul 21. Ann Hum Genet. 2011. PMID: 21777205 Free PMC article.
154 results