Kober DL - Search Results

1

TREM2-Ligand Interactions in Health and Disease.

Kober DL, Brett TJ. Kober DL, et al. J Mol Biol. 2017 Jun 2;429(11):1607-1629. doi: 10.1016/j.jmb.2017.04.004. Epub 2017 Apr 19. J Mol Biol. 2017. PMID: 28432014 Free PMC article. Review.

2

Preparation, crystallization, and preliminary crystallographic analysis of wild-type and mutant human TREM-2 ectodomains linked to neurodegenerative and inflammatory diseases.

Kober DL, Wanhainen KM, Johnson BM, Randolph DT, Holtzman MJ, Brett TJ. Kober DL, et al. Protein Expr Purif. 2014 Apr;96:32-8. doi: 10.1016/j.pep.2014.01.015. Epub 2014 Feb 7. Protein Expr Purif. 2014. PMID: 24508568 Free PMC article.

3

TREM-2 promotes macrophage survival and lung disease after respiratory viral infection.

Wu K, Byers DE, Jin X, Agapov E, Alexander-Brett J, Patel AC, Cella M, Gilfilan S, Colonna M, Kober DL, Brett TJ, Holtzman MJ. Wu K, et al. Among authors: kober dl. J Exp Med. 2015 May 4;212(5):681-97. doi: 10.1084/jem.20141732. Epub 2015 Apr 20. J Exp Med. 2015. PMID: 25897174 Free PMC article.

4

First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes.

Yurtsever Z, Patel DA, Kober DL, Su A, Miller CA, Romero AG, Holtzman MJ, Brett TJ. Yurtsever Z, et al. Among authors: kober dl. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2335-2344. doi: 10.1016/j.bbagen.2016.06.023. Epub 2016 Jun 29. Biochim Biophys Acta. 2016. PMID: 27369736 Free PMC article.

5

Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms.

Kober DL, Alexander-Brett JM, Karch CM, Cruchaga C, Colonna M, Holtzman MJ, Brett TJ. Kober DL, et al. Elife. 2016 Dec 20;5:e20391. doi: 10.7554/eLife.20391. Elife. 2016. PMID: 27995897 Free PMC article.

6

Limiting Respiratory Viral Infection by Targeting Antiviral and Immunological Functions of BST-2/Tetherin: Knowledge and Gaps.

Berry KN, Kober DL, Su A, Brett TJ. Berry KN, et al. Among authors: kober dl. Bioessays. 2018 Oct;40(10):e1800086. doi: 10.1002/bies.201800086. Epub 2018 Aug 16. Bioessays. 2018. PMID: 30113067 Free PMC article. Review.

7

YbtT is a low-specificity type II thioesterase that maintains production of the metallophore yersiniabactin in pathogenic enterobacteria.

Ohlemacher SI, Xu Y, Kober DL, Malik M, Nix JC, Brett TJ, Henderson JP. Ohlemacher SI, et al. Among authors: kober dl. J Biol Chem. 2018 Dec 21;293(51):19572-19585. doi: 10.1074/jbc.RA118.005752. Epub 2018 Oct 24. J Biol Chem. 2018. PMID: 30355735 Free PMC article.

8

Functional insights from biophysical study of TREM2 interactions with apoE and Aβ_1-42.

Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. Kober DL, et al. Alzheimers Dement. 2020 Oct 8:10.1002/alz.12194. doi: 10.1002/alz.12194. Online ahead of print. Alzheimers Dement. 2020. PMID: 33090700 Free PMC article.

9

SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P.

Hendrix S, Tan JME, Ndoj K, Kingma J, Valiloo M, Zijlstra LF, Ottenhoff R, Seidah NG, Loregger A, Kober DL, Zelcer N. Hendrix S, et al. Among authors: kober dl. Mol Cell Biol. 2024;44(4):123-137. doi: 10.1080/10985549.2024.2348711. Epub 2024 May 15. Mol Cell Biol. 2024. PMID: 38747374

10

Efficient Mammalian Cell Expression and Single-step Purification of Extracellular Glycoproteins for Crystallization.

Kober DL, Yurtsever Z, Brett TJ. Kober DL, et al. J Vis Exp. 2015 Dec 23;(106):e53445. doi: 10.3791/53445. J Vis Exp. 2015. PMID: 26780656 Free PMC article.

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