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DNA single-strand break-induced DNA damage response causes heart failure.
Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I. Higo T, et al. Among authors: mckinnon pj. Nat Commun. 2017 Apr 24;8:15104. doi: 10.1038/ncomms15104. Nat Commun. 2017. PMID: 28436431 Free PMC article.
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Hoch NC, Hanzlikova H, Rulten SL, Tétreault M, Komulainen E, Ju L, Hornyak P, Zeng Z, Gittens W, Rey SA, Staras K, Mancini GM, McKinnon PJ, Wang ZQ, Wagner JD; Care4Rare Canada Consortium; Yoon G, Caldecott KW. Hoch NC, et al. Among authors: mckinnon pj. Nature. 2017 Jan 5;541(7635):87-91. doi: 10.1038/nature20790. Epub 2016 Dec 21. Nature. 2017. PMID: 28002403 Free PMC article.
DNA strand break repair and human genetic disease.
McKinnon PJ, Caldecott KW. McKinnon PJ, et al. Annu Rev Genomics Hum Genet. 2007;8:37-55. doi: 10.1146/annurev.genom.7.080505.115648. Annu Rev Genomics Hum Genet. 2007. PMID: 17887919 Review.
DNA strand breaks, neurodegeneration and aging in the brain.
Katyal S, McKinnon PJ. Katyal S, et al. Among authors: mckinnon pj. Mech Ageing Dev. 2008 Jul-Aug;129(7-8):483-91. doi: 10.1016/j.mad.2008.03.008. Epub 2008 Mar 25. Mech Ageing Dev. 2008. PMID: 18455751 Free PMC article. Review.
DNA double-strand break repair and development.
Phillips ER, McKinnon PJ. Phillips ER, et al. Among authors: mckinnon pj. Oncogene. 2007 Dec 10;26(56):7799-808. doi: 10.1038/sj.onc.1210877. Oncogene. 2007. PMID: 18066093 Review.
139 results