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The Use of Non-Variant Sites to Improve the Clinical Assessment of Whole-Genome Sequence Data.
Ferrarini A, Xumerle L, Griggio F, Garonzi M, Cantaloni C, Centomo C, Vargas SM, Descombes P, Marquis J, Collino S, Franceschi C, Garagnani P, Salisbury BA, Harvey JM, Delledonne M. Ferrarini A, et al. Among authors: descombes p. PLoS One. 2015 Jul 6;10(7):e0132180. doi: 10.1371/journal.pone.0132180. eCollection 2015. PLoS One. 2015. PMID: 26147798 Free PMC article.
Medium-chain fatty acids inhibit mitochondrial metabolism in astrocytes promoting astrocyte-neuron lactate and ketone body shuttle systems.
Thevenet J, De Marchi U, Domingo JS, Christinat N, Bultot L, Lefebvre G, Sakamoto K, Descombes P, Masoodi M, Wiederkehr A. Thevenet J, et al. Among authors: descombes p. FASEB J. 2016 May;30(5):1913-26. doi: 10.1096/fj.201500182. Epub 2016 Feb 2. FASEB J. 2016. PMID: 26839375
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop of the NAD(P)H signal in astrocytes, but not in neurons. Despite the observed effects on mitochondrial function, MCFAs did not lower intrac …
Using single-cell imaging, we observed an acute pronounced reduction of the mitochondrial electrical potential and a concomitant drop of the …
Oral Phage Therapy of Acute Bacterial Diarrhea With Two Coliphage Preparations: A Randomized Trial in Children From Bangladesh.
Sarker SA, Sultana S, Reuteler G, Moine D, Descombes P, Charton F, Bourdin G, McCallin S, Ngom-Bru C, Neville T, Akter M, Huq S, Qadri F, Talukdar K, Kassam M, Delley M, Loiseau C, Deng Y, El Aidy S, Berger B, Brüssow H. Sarker SA, et al. Among authors: descombes p. EBioMedicine. 2016 Jan 5;4:124-37. doi: 10.1016/j.ebiom.2015.12.023. eCollection 2016 Feb. EBioMedicine. 2016. PMID: 26981577 Free PMC article. Clinical Trial.
Genome Sequence of Lactobacillus fermentum Strain NCC2970 (CNCM I-5068).
Barretto C, Ngom-Bru C, Genevaz A, Fournier C, Moine D, Kassam M, Iltis A, Sagory-Zalkind P, Ciron PE, Faucherand G, Descombes P, Duboux S. Barretto C, et al. Among authors: descombes p. Genome Announc. 2016 Nov 17;4(6):e01254-16. doi: 10.1128/genomeA.01254-16. Genome Announc. 2016. PMID: 27856580 Free PMC article.
Centenarians as extreme phenotypes: An ecological perspective to get insight into the relationship between the genetics of longevity and age-associated diseases.
Giuliani C, Pirazzini C, Delledonne M, Xumerle L, Descombes P, Marquis J, Mengozzi G, Monti D, Bellizzi D, Passarino G, Luiselli D, Franceschi C, Garagnani P. Giuliani C, et al. Among authors: descombes p. Mech Ageing Dev. 2017 Jul;165(Pt B):195-201. doi: 10.1016/j.mad.2017.02.007. Epub 2017 Feb 27. Mech Ageing Dev. 2017. PMID: 28242236 Review.
One-carbon metabolism, cognitive impairment and CSF measures of Alzheimer pathology: homocysteine and beyond.
Dayon L, Guiraud SP, Corthésy J, Da Silva L, Migliavacca E, Tautvydaitė D, Oikonomidi A, Moullet B, Henry H, Métairon S, Marquis J, Descombes P, Collino S, Martin FJ, Montoliu I, Kussmann M, Wojcik J, Bowman GL, Popp J. Dayon L, et al. Among authors: descombes p. Alzheimers Res Ther. 2017 Jun 17;9(1):43. doi: 10.1186/s13195-017-0270-x. Alzheimers Res Ther. 2017. PMID: 28623948 Free PMC article.
172 results