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Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.
Tavernier SJ, Osorio F, Vandersarren L, Vetters J, Vanlangenakker N, Van Isterdael G, Vergote K, De Rycke R, Parthoens E, van de Laar L, Iwawaki T, Del Valle JR, Hu CC, Lambrecht BN, Janssens S. Tavernier SJ, et al. Among authors: iwawaki t. Nat Cell Biol. 2017 Jun;19(6):698-710. doi: 10.1038/ncb3518. Epub 2017 May 1. Nat Cell Biol. 2017. PMID: 28459443 Free PMC article.
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.
Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L. Sun S, et al. Among authors: iwawaki t. Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9. Nat Cell Biol. 2015. PMID: 26551274 Free PMC article.
IRE1 signaling exacerbates Alzheimer's disease pathogenesis.
Duran-Aniotz C, Cornejo VH, Espinoza S, Ardiles ÁO, Medinas DB, Salazar C, Foley A, Gajardo I, Thielen P, Iwawaki T, Scheper W, Soto C, Palacios AG, Hoozemans JJM, Hetz C. Duran-Aniotz C, et al. Among authors: iwawaki t. Acta Neuropathol. 2017 Sep;134(3):489-506. doi: 10.1007/s00401-017-1694-x. Epub 2017 Mar 24. Acta Neuropathol. 2017. PMID: 28341998
IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A.
Urra H, Henriquez DR, Cánovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic Á, Gonzalez-Billault C, Hetz C. Urra H, et al. Among authors: iwawaki t. Nat Cell Biol. 2018 Aug;20(8):942-953. doi: 10.1038/s41556-018-0141-0. Epub 2018 Jul 16. Nat Cell Biol. 2018. PMID: 30013108
144 results