Mårtensson LG - Search Results

1

One amino acid makes a difference-Characterization of a new TPMT allele and the influence of SAM on TPMT stability.

Iu YPH, Helander S, Kahlin AZ, Cheng CW, Shek CC, Leung MH, Wallner B, Mårtensson LG, Appell ML. Iu YPH, et al. Among authors: martensson lg. Sci Rep. 2017 May 2;7:46428. doi: 10.1038/srep46428. Sci Rep. 2017. PMID: 28462921 Free PMC article.

2

Characterization of a novel sequence variant, TPMT*28, in the human thiopurine methyltransferase gene.

Appell ML, Wennerstrand P, Peterson C, Hertervig E, Mårtensson LG. Appell ML, et al. Among authors: martensson lg. Pharmacogenet Genomics. 2010 Nov;20(11):700-7. doi: 10.1097/FPC.0b013e3283402ee4. Pharmacogenet Genomics. 2010. PMID: 20881512

3

Structural characteristics determine the cause of the low enzyme activity of two thiopurine S-methyltransferase allelic variants: a biophysical characterization of TPMT*2 and TPMT*5.

Wennerstrand P, Dametto P, Hennig J, Klingstedt T, Skoglund K, Appell ML, Mårtensson LG. Wennerstrand P, et al. Among authors: martensson lg. Biochemistry. 2012 Jul 31;51(30):5912-20. doi: 10.1021/bi300377d. Epub 2012 Jul 16. Biochemistry. 2012. PMID: 22747506

4

Methotrexate binds to recombinant thiopurine S-methyltransferase and inhibits enzyme activity after high-dose infusions in childhood leukaemia.

Wennerstrand P, Mårtensson LG, Söderhäll S, Zimdahl A, Appell ML. Wennerstrand P, et al. Among authors: martensson lg. Eur J Clin Pharmacol. 2013 Sep;69(9):1641-9. doi: 10.1007/s00228-013-1521-9. Epub 2013 May 10. Eur J Clin Pharmacol. 2013. PMID: 23660772 Clinical Trial.

5

Robust and convenient analysis of protein thermal and chemical stability.

Niklasson M, Andresen C, Helander S, Roth MG, Zimdahl Kahlin A, Lindqvist Appell M, Mårtensson LG, Lundström P. Niklasson M, et al. Among authors: martensson lg. Protein Sci. 2015 Dec;24(12):2055-62. doi: 10.1002/pro.2809. Epub 2015 Oct 10. Protein Sci. 2015. PMID: 26402034 Free PMC article.

6

In Vitro Protein Stability of Two Naturally Occurring Thiopurine S-Methyltransferase Variants: Biophysical Characterization of TPMT*6 and TPMT*8.

Wennerstrand P, Blissing A, Mårtensson LG. Wennerstrand P, et al. Among authors: martensson lg. ACS Omega. 2017 Aug 31;2(8):4991-4999. doi: 10.1021/acsomega.7b00801. Epub 2017 Aug 28. ACS Omega. 2017. PMID: 30023734 Free PMC article.

7

Comprehensive study of thiopurine methyltransferase genotype, phenotype, and genotype-phenotype discrepancies in Sweden.

Zimdahl Kahlin A, Helander S, Skoglund K, Söderkvist P, Mårtensson LG, Appell ML. Zimdahl Kahlin A, et al. Among authors: martensson lg. Biochem Pharmacol. 2019 Jun;164:263-272. doi: 10.1016/j.bcp.2019.04.020. Epub 2019 Apr 18. Biochem Pharmacol. 2019. PMID: 31005613 Free article.

8

Pharmacogenetic studies of thiopurine methyltransferase genotype-phenotype concordance and effect of methotrexate on thiopurine metabolism.

Zimdahl Kahlin A, Helander S, Wennerstrand P, Vikingsson S, Mårtensson LG, Appell ML. Zimdahl Kahlin A, et al. Among authors: martensson lg. Basic Clin Pharmacol Toxicol. 2021 Jan;128(1):52-65. doi: 10.1111/bcpt.13483. Epub 2020 Sep 14. Basic Clin Pharmacol Toxicol. 2021. PMID: 32865889 Free PMC article. Review.

9

Small-angle x-ray and neutron scattering of MexR and its complex with DNA supports a conformational selection binding model.

Caporaletti F, Pietras Z, Morad V, Mårtensson LG, Gabel F, Wallner B, Martel A, Sunnerhagen M. Caporaletti F, et al. Among authors: martensson lg. Biophys J. 2023 Jan 17;122(2):408-418. doi: 10.1016/j.bpj.2022.11.2949. Epub 2022 Dec 5. Biophys J. 2023. PMID: 36474441 Free PMC article.

10

Methylation of selenocysteine catalysed by thiopurine S-methyltransferase.

Urbančič D, Kotar A, Šmid A, Jukič M, Gobec S, Mårtensson LG, Plavec J, Mlinarič-Raščan I. Urbančič D, et al. Among authors: martensson lg. Biochim Biophys Acta Gen Subj. 2019 Jan;1863(1):182-190. doi: 10.1016/j.bbagen.2018.10.002. Epub 2018 Oct 9. Biochim Biophys Acta Gen Subj. 2019. PMID: 30308221 Free article.

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