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The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings.
Saccone NL, Baurley JW, Bergen AW, David SP, Elliott HR, Foreman MG, Kaprio J, Piasecki TM, Relton CL, Zawertailo L, Bierut LJ, Tyndale RF, Chen LS; Genetics and Treatment Networks of the Society for Research on Nicotine and Tobacco (SRNT). Saccone NL, et al. Among authors: tyndale rf. Nicotine Tob Res. 2018 Mar 6;20(4):403-413. doi: 10.1093/ntr/ntx096. Nicotine Tob Res. 2018. PMID: 28472521 Free PMC article. Review.
A common genetic defect in nicotine metabolism decreases risk for dependence and lowers cigarette consumption.
Tyndale RF, Pianezza ML, Sellers EM. Tyndale RF, et al. Nicotine Tob Res. 1999;1 Suppl 2:S63-7; discussion S69-70. doi: 10.1080/14622299050011831. Nicotine Tob Res. 1999. PMID: 11768189 Review.
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if dependent, how impairment of the CYP2A6 gene function decreases the number of cigarettes consumed by smokers (Pianezza M, Sellers EM, Tyndale
This paper outlines how genetic variation in the CYP2A6 gene may protect individuals from becoming nicotine-dependent smokers, and if depend …
Genetic influences on smoking: a brief review.
Al Koudsi N, Tyndale RF. Al Koudsi N, et al. Among authors: tyndale rf. Ther Drug Monit. 2005 Dec;27(6):704-9. doi: 10.1097/01.ftd.0000179842.63515.c6. Ther Drug Monit. 2005. PMID: 16404798 Review.
Non-nicotinic therapies for smoking cessation.
Siu EC, Tyndale RF. Siu EC, et al. Among authors: tyndale rf. Annu Rev Pharmacol Toxicol. 2007;47:541-64. doi: 10.1146/annurev.pharmtox.47.120505.105354. Annu Rev Pharmacol Toxicol. 2007. PMID: 17209799 Review.
Nicotinic acetylcholine receptor beta2 subunit gene implicated in a systems-based candidate gene study of smoking cessation.
Conti DV, Lee W, Li D, Liu J, Van Den Berg D, Thomas PD, Bergen AW, Swan GE, Tyndale RF, Benowitz NL, Lerman C; Pharmacogenetics of Nicotine Addiction and Treatment Consortium. Conti DV, et al. Among authors: tyndale rf. Hum Mol Genet. 2008 Sep 15;17(18):2834-48. doi: 10.1093/hmg/ddn181. Epub 2008 Jul 1. Hum Mol Genet. 2008. PMID: 18593715 Free PMC article. Clinical Trial.
441 results