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Negative selection in humans and fruit flies involves synergistic epistasis.
Sohail M, Vakhrusheva OA, Sul JH, Pulit SL, Francioli LC; Genome of the Netherlands Consortium; Alzheimer’s Disease Neuroimaging Initiative; van den Berg LH, Veldink JH, de Bakker PIW, Bazykin GA, Kondrashov AS, Sunyaev SR. Sohail M, et al. Among authors: sunyaev sr. Science. 2017 May 5;356(6337):539-542. doi: 10.1126/science.aah5238. Science. 2017. PMID: 28473589 Free PMC article.
Prediction of deleterious human alleles.
Sunyaev S, Ramensky V, Koch I, Lathe W 3rd, Kondrashov AS, Bork P. Sunyaev S, et al. Hum Mol Genet. 2001 Mar 15;10(6):591-7. doi: 10.1093/hmg/10.6.591. Hum Mol Genet. 2001. PMID: 11230178
Dobzhansky-Muller incompatibilities in protein evolution.
Kondrashov AS, Sunyaev S, Kondrashov FA. Kondrashov AS, et al. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):14878-83. doi: 10.1073/pnas.232565499. Epub 2002 Oct 28. Proc Natl Acad Sci U S A. 2002. PMID: 12403824 Free PMC article.
Erratum.
Schmidt S, Gerasimova A, Kondrashov FA, Adzhubei IA, Kondrashov AS, Sunyaev S. Schmidt S, et al. PLoS Genet. 2008 Dec;4(12):10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. doi: 10.1371/annotation/a81b1fab-890c-447b-a308-5bc8ca3eb21d. Epub 2008 Dec 10. PLoS Genet. 2008. PMID: 19096535 Free PMC article.
A method and server for predicting damaging missense mutations.
Adzhubei IA, Schmidt S, Peshkin L, Ramensky VE, Gerasimova A, Bork P, Kondrashov AS, Sunyaev SR. Adzhubei IA, et al. Among authors: sunyaev sr. Nat Methods. 2010 Apr;7(4):248-9. doi: 10.1038/nmeth0410-248. Nat Methods. 2010. PMID: 20354512 Free PMC article. No abstract available.
Pooled association tests for rare variants in exon-resequencing studies.
Price AL, Kryukov GV, de Bakker PI, Purcell SM, Staples J, Wei LJ, Sunyaev SR. Price AL, et al. Among authors: sunyaev sr. Am J Hum Genet. 2010 Jun 11;86(6):832-8. doi: 10.1016/j.ajhg.2010.04.005. Epub 2010 May 13. Am J Hum Genet. 2010. PMID: 20471002 Free PMC article.
Deleterious alleles in the human genome are on average younger than neutral alleles of the same frequency.
Kiezun A, Pulit SL, Francioli LC, van Dijk F, Swertz M, Boomsma DI, van Duijn CM, Slagboom PE, van Ommen GJ, Wijmenga C; Genome of the Netherlands Consortium; de Bakker PI, Sunyaev SR. Kiezun A, et al. Among authors: sunyaev sr. PLoS Genet. 2013;9(2):e1003301. doi: 10.1371/journal.pgen.1003301. Epub 2013 Feb 28. PLoS Genet. 2013. PMID: 23468643 Free PMC article.
194 results