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Genome-scale measurement of off-target activity using Cas9 toxicity in high-throughput screens.
Nat Commun. 2017 May 5;8:15178. doi: 10.1038/ncomms15178.
Nat Commun. 2017.
PMID: 28474669
Free PMC article.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.
Han K, Jeng EE, Hess GT, Morgens DW, Li A, Bassik MC.
Han K, et al. Among authors: jeng ee.
Nat Biotechnol. 2017 May;35(5):463-474. doi: 10.1038/nbt.3834. Epub 2017 Mar 20.
Nat Biotechnol. 2017.
PMID: 28319085
Free PMC article.
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Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen.
Jeng EE, Bhadkamkar V, Ibe NU, Gause H, Jiang L, Chan J, Jian R, Jimenez-Morales D, Stevenson E, Krogan NJ, Swaney DL, Snyder MP, Mukherjee S, Bassik MC.
Jeng EE, et al.
Cell Host Microbe. 2019 Oct 9;26(4):551-563.e6. doi: 10.1016/j.chom.2019.08.017. Epub 2019 Sep 17.
Cell Host Microbe. 2019.
PMID: 31540829
Free PMC article.
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Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.
Kelly MR, Kostyrko K, Han K, Mooney NA, Jeng EE, Spees K, Dinh PT, Abbott KL, Gwinn DM, Sweet-Cordero EA, Bassik MC, Jackson PK.
Kelly MR, et al. Among authors: jeng ee.
Cancer Discov. 2020 Dec;10(12):1950-1967. doi: 10.1158/2159-8290.CD-19-1274. Epub 2020 Jul 29.
Cancer Discov. 2020.
PMID: 32727735
Free PMC article.
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The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D.
Chaikovsky AC, Li C, Jeng EE, Loebell S, Lee MC, Murray CW, Cheng R, Demeter J, Swaney DL, Chen SH, Newton BW, Johnson JR, Drainas AP, Shue YT, Seoane JA, Srinivasan P, He A, Yoshida A, Hipkins SQ, McCrea E, Poltorack CD, Krogan NJ, Diehl JA, Kong C, Jackson PK, Curtis C, Petrov DA, Bassik MC, Winslow MM, Sage J.
Chaikovsky AC, et al. Among authors: jeng ee.
Nature. 2021 Apr;592(7856):794-798. doi: 10.1038/s41586-021-03474-7. Epub 2021 Apr 14.
Nature. 2021.
PMID: 33854239
Free PMC article.
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Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages.
Cohen A, Jeng EE, Voorhies M, Symington J, Ali N, Rodriguez RA, Bassik MC, Sil A.
Cohen A, et al. Among authors: jeng ee.
PLoS Pathog. 2022 Sep 29;18(9):e1010237. doi: 10.1371/journal.ppat.1010237. eCollection 2022 Sep.
PLoS Pathog. 2022.
PMID: 36174103
Free PMC article.
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CBP Modulates Sensitivity to Dasatinib in Pre-BCR+ Acute Lymphoblastic Leukemia.
Duque-Afonso J, Lin CH, Han K, Morgens DW, Jeng EE, Weng Z, Jeong J, Wong SHK, Zhu L, Wei MC, Chae HD, Schrappe M, Cario G, Duyster J, Xiao X, Sakamoto KM, Bassik MC, Cleary ML.
Duque-Afonso J, et al. Among authors: jeng ee.
Cancer Res. 2018 Nov 15;78(22):6497-6508. doi: 10.1158/0008-5472.CAN-18-1703. Epub 2018 Sep 27.
Cancer Res. 2018.
PMID: 30262461
Free PMC article.
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Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.
Raisner R, Kharbanda S, Jin L, Jeng E, Chan E, Merchant M, Haverty PM, Bainer R, Cheung T, Arnott D, Flynn EM, Romero FA, Magnuson S, Gascoigne KE.
Raisner R, et al.
Cell Rep. 2018 Aug 14;24(7):1722-1729. doi: 10.1016/j.celrep.2018.07.041.
Cell Rep. 2018.
PMID: 30110629
Free article.
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