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Intrahepatic CD206+ macrophages contribute to inflammation in advanced viral-related liver disease.
Tan-Garcia A, Wai LE, Zheng D, Ceccarello E, Jo J, Banu N, Khakpoor A, Chia A, Tham CYL, Tan AT, Hong M, Keng CT, Rivino L, Tan KC, Lee KH, Lim SG, Newell EW, Pavelka N, Chen J, Ginhoux F, Chen Q, Bertoletti A, Dutertre CA. Tan-Garcia A, et al. Among authors: chen j, chen q. J Hepatol. 2017 Sep;67(3):490-500. doi: 10.1016/j.jhep.2017.04.023. Epub 2017 May 5. J Hepatol. 2017. PMID: 28483682
Characterisation of liver pathogenesis, human immune responses and drug testing in a humanised mouse model of HCV infection.
Keng CT, Sze CW, Zheng D, Zheng Z, Yong KS, Tan SQ, Ong JJ, Tan SY, Loh E, Upadya MH, Kuick CH, Hotta H, Lim SG, Tan TC, Chang KT, Hong W, Chen J, Tan YJ, Chen Q. Keng CT, et al. Among authors: chen j, chen q. Gut. 2016 Oct;65(10):1744-53. doi: 10.1136/gutjnl-2014-307856. Epub 2015 Jul 6. Gut. 2016. PMID: 26149491 Free PMC article.
Mapping the human DC lineage through the integration of high-dimensional techniques.
See P, Dutertre CA, Chen J, Günther P, McGovern N, Irac SE, Gunawan M, Beyer M, Händler K, Duan K, Sumatoh HRB, Ruffin N, Jouve M, Gea-Mallorquí E, Hennekam RCM, Lim T, Yip CC, Wen M, Malleret B, Low I, Shadan NB, Fen CFS, Tay A, Lum J, Zolezzi F, Larbi A, Poidinger M, Chan JKY, Chen Q, Rénia L, Haniffa M, Benaroch P, Schlitzer A, Schultze JL, Newell EW, Ginhoux F. See P, et al. Among authors: chen j, chen q. Science. 2017 Jun 9;356(6342):eaag3009. doi: 10.1126/science.aag3009. Epub 2017 May 4. Science. 2017. PMID: 28473638 Free PMC article.
Development of a new patient-derived xenograft humanised mouse model to study human-specific tumour microenvironment and immunotherapy.
Zhao Y, Shuen TWH, Toh TB, Chan XY, Liu M, Tan SY, Fan Y, Yang H, Lyer SG, Bonney GK, Loh E, Chang KTE, Tan TC, Zhai W, Chan JKY, Chow EK, Chee CE, Lee GH, Dan YY, Chow PK, Toh HC, Lim SG, Chen Q. Zhao Y, et al. Among authors: chen q. Gut. 2018 Oct;67(10):1845-1854. doi: 10.1136/gutjnl-2017-315201. Epub 2018 Mar 30. Gut. 2018. PMID: 29602780 Free PMC article.
Liver fibrosis and CD206+ macrophage accumulation are suppressed by anti-GM-CSF therapy.
Tan-Garcia A, Lai F, Sheng Yeong JP, Irac SE, Ng PY, Msallam R, Tatt Lim JC, Wai LE, Tham CYL, Choo SP, Lim T, Young DY, D'Ambrosio R, Degasperi E, Perbellini R, Newell E, Le Bert N, Ginhoux F, Bertoletti A, Chen Q, Dutertre CA. Tan-Garcia A, et al. Among authors: chen q. JHEP Rep. 2019 Dec 6;2(1):100062. doi: 10.1016/j.jhepr.2019.11.006. eCollection 2020 Feb. JHEP Rep. 2019. PMID: 32039403 Free PMC article.
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