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Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade.
Shah JA, Patel MS, Elias N, Navarro-Alvarez N, Rosales I, Wilkinson RA, Louras NJ, Hertl M, Fishman JA, Colvin RB, Cosimi AB, Markmann JF, Sachs DH, Vagefi PA. Shah JA, et al. Among authors: louras nj. Am J Transplant. 2017 Aug;17(8):2178-2185. doi: 10.1111/ajt.14341. Epub 2017 Jun 6. Am J Transplant. 2017. PMID: 28489305 Free PMC article.
Liver xenotransplantation.
Patel MS, Louras N, Vagefi PA. Patel MS, et al. Curr Opin Organ Transplant. 2017 Dec;22(6):535-540. doi: 10.1097/MOT.0000000000000459. Curr Opin Organ Transplant. 2017. PMID: 28817400 Free PMC article. Review.
GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.
Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. Watanabe H, et al. Among authors: louras nj. Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12. Xenotransplantation. 2018. PMID: 29527745 Free PMC article.