De Strooper B - Search Results

1

Tau association with synaptic vesicles causes presynaptic dysfunction.

Zhou L, McInnes J, Wierda K, Holt M, Herrmann AG, Jackson RJ, Wang YC, Swerts J, Beyens J, Miskiewicz K, Vilain S, Dewachter I, Moechars D, De Strooper B, Spires-Jones TL, De Wit J, Verstreken P. Zhou L, et al. Among authors: de strooper b, de wit j. Nat Commun. 2017 May 11;8:15295. doi: 10.1038/ncomms15295. Nat Commun. 2017. PMID: 28492240 Free PMC article.

2

Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes.

De Strooper B, Creemers JW, Moechars D, Huylebroeck D, Van De Ven WJ, Van Leuven F, Van den Berghe H. De Strooper B, et al. Biochim Biophys Acta. 1995 Jan 19;1246(2):185-8. doi: 10.1016/0167-4838(94)00194-l. Biochim Biophys Acta. 1995. PMID: 7819286

3

Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease.

De Strooper B, Craessaerts K, Dewachter I, Moechars D, Greenberg B, Van Leuven F, Van den Berghe H. De Strooper B, et al. J Biol Chem. 1995 Feb 24;270(8):4058-65. doi: 10.1074/jbc.270.8.4058. J Biol Chem. 1995. PMID: 7876155 Free article.

4

Expression in brain of amyloid precursor protein mutated in the alpha-secretase site causes disturbed behavior, neuronal degeneration and premature death in transgenic mice.

Moechars D, Lorent K, De Strooper B, Dewachter I, Van Leuven F. Moechars D, et al. Among authors: de strooper b. EMBO J. 1996 Mar 15;15(6):1265-74. EMBO J. 1996. PMID: 8635459 Free PMC article.

5

Transgenic mice expressing an alpha-secretion mutant of the amyloid precursor protein in the brain develop a progressive CNS disorder.

Moechars D, Lorent K, Dewachter I, Baekelandt V, De Strooper B, Van Leuven F. Moechars D, et al. Among authors: de strooper b. Behav Brain Res. 1998 Sep;95(1):55-64. doi: 10.1016/s0166-4328(97)00210-6. Behav Brain Res. 1998. PMID: 9754877

6

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.

Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B. Morais VA, et al. Among authors: de strooper b. EMBO Mol Med. 2009 May;1(2):99-111. doi: 10.1002/emmm.200900006. EMBO Mol Med. 2009. PMID: 20049710 Free PMC article.

7

Neurons generated from APP/APLP1/APLP2 triple knockout embryonic stem cells behave normally in vitro and in vivo: lack of evidence for a cell autonomous role of the amyloid precursor protein in neuronal differentiation.

Bergmans BA, Shariati SA, Habets RL, Verstreken P, Schoonjans L, Müller U, Dotti CG, De Strooper B. Bergmans BA, et al. Among authors: de strooper b. Stem Cells. 2010 Mar 31;28(3):399-406. doi: 10.1002/stem.296. Stem Cells. 2010. PMID: 20049903

8

Inhibition of beta-secretase in vivo via antibody binding to unique loops (D and F) of BACE1.

Zhou L, Chávez-Gutiérrez L, Bockstael K, Sannerud R, Annaert W, May PC, Karran E, De Strooper B. Zhou L, et al. Among authors: de strooper b. J Biol Chem. 2011 Mar 11;286(10):8677-8687. doi: 10.1074/jbc.M110.194860. Epub 2011 Jan 5. J Biol Chem. 2011. PMID: 21209097 Free PMC article.

9

Amyloid precursor protein mutation E682K at the alternative β-secretase cleavage β'-site increases Aβ generation.

Zhou L, Brouwers N, Benilova I, Vandersteen A, Mercken M, Van Laere K, Van Damme P, Demedts D, Van Leuven F, Sleegers K, Broersen K, Van Broeckhoven C, Vandenberghe R, De Strooper B. Zhou L, et al. Among authors: de strooper b. EMBO Mol Med. 2011 May;3(5):291-302. doi: 10.1002/emmm.201100138. Epub 2011 Apr 15. EMBO Mol Med. 2011. PMID: 21500352 Free PMC article.

10

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P. Vilain S, et al. Among authors: de strooper b. PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5. PLoS Genet. 2012. PMID: 22242018 Free PMC article.

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