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Page 1
Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.
Dewey FE, Gusarova V, Dunbar RL, O'Dushlaine C, Schurmann C, Gottesman O, McCarthy S, Van Hout CV, Bruse S, Dansky HM, Leader JB, Murray MF, Ritchie MD, Kirchner HL, Habegger L, Lopez A, Penn J, Zhao A, Shao W, Stahl N, Murphy AJ, Hamon S, Bouzelmat A, Zhang R, Shumel B, Pordy R, Gipe D, Herman GA, Sheu WHH, Lee IT, Liang KW, Guo X, Rotter JI, Chen YI, Kraus WE, Shah SH, Damrauer S, Small A, Rader DJ, Wulff AB, Nordestgaard BG, Tybjærg-Hansen A, van den Hoek AM, Princen HMG, Ledbetter DH, Carey DJ, Overton JD, Reid JG, Sasiela WJ, Banerjee P, Shuldiner AR, Borecki IB, Teslovich TM, Yancopoulos GD, Mellis SJ, Gromada J, Baras A. Dewey FE, et al. Among authors: murphy aj. N Engl J Med. 2017 Jul 20;377(3):211-221. doi: 10.1056/NEJMoa1612790. Epub 2017 May 24. N Engl J Med. 2017. PMID: 28538136 Free PMC article. Clinical Trial.
VEGF-mediated inflammation precedes angiogenesis in adult brain.
Croll SD, Ransohoff RM, Cai N, Zhang Q, Martin FJ, Wei T, Kasselman LJ, Kintner J, Murphy AJ, Yancopoulos GD, Wiegand SJ. Croll SD, et al. Among authors: murphy aj. Exp Neurol. 2004 Jun;187(2):388-402. doi: 10.1016/j.expneurol.2004.02.010. Exp Neurol. 2004. PMID: 15144865
The loss-of-allele assay for ES cell screening and mouse genotyping.
Frendewey D, Chernomorsky R, Esau L, Om J, Xue Y, Murphy AJ, Yancopoulos GD, Valenzuela DM. Frendewey D, et al. Among authors: murphy aj. Methods Enzymol. 2010;476:295-307. doi: 10.1016/S0076-6879(10)76017-1. Methods Enzymol. 2010. PMID: 20691873
Ongoing Dll4-Notch signaling is required for T-cell homeostasis in the adult thymus.
Billiard F, Kirshner JR, Tait M, Danave A, Taheri S, Zhang W, Waite JC, Olson K, Chen G, Coetzee S, Hylton D, Murphy AJ, Yancopoulos GD, Thurston G, Skokos D. Billiard F, et al. Among authors: murphy aj. Eur J Immunol. 2011 Aug;41(8):2207-16. doi: 10.1002/eji.201041343. Epub 2011 Jul 4. Eur J Immunol. 2011. PMID: 21598246 Free article.
Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice.
Billiard F, Lobry C, Darrasse-Jèze G, Waite J, Liu X, Mouquet H, DaNave A, Tait M, Idoyaga J, Leboeuf M, Kyratsous CA, Burton J, Kalter J, Klinakis A, Zhang W, Thurston G, Merad M, Steinman RM, Murphy AJ, Yancopoulos GD, Aifantis I, Skokos D. Billiard F, et al. Among authors: murphy aj. J Exp Med. 2012 May 7;209(5):1011-28. doi: 10.1084/jem.20111615. Epub 2012 Apr 30. J Exp Med. 2012. PMID: 22547652 Free PMC article.
Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice.
Murphy AJ, Macdonald LE, Stevens S, Karow M, Dore AT, Pobursky K, Huang TT, Poueymirou WT, Esau L, Meola M, Mikulka W, Krueger P, Fairhurst J, Valenzuela DM, Papadopoulos N, Yancopoulos GD. Murphy AJ, et al. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5153-8. doi: 10.1073/pnas.1324022111. Epub 2014 Mar 25. Proc Natl Acad Sci U S A. 2014. PMID: 24706856 Free PMC article.
Precise and in situ genetic humanization of 6 Mb of mouse immunoglobulin genes.
Macdonald LE, Karow M, Stevens S, Auerbach W, Poueymirou WT, Yasenchak J, Frendewey D, Valenzuela DM, Giallourakis CC, Alt FW, Yancopoulos GD, Murphy AJ. Macdonald LE, et al. Among authors: murphy aj. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5147-52. doi: 10.1073/pnas.1323896111. Epub 2014 Mar 25. Proc Natl Acad Sci U S A. 2014. PMID: 24706858 Free PMC article.
ANGPTL8/betatrophin does not control pancreatic beta cell expansion.
Gusarova V, Alexa CA, Na E, Stevis PE, Xin Y, Bonner-Weir S, Cohen JC, Hobbs HH, Murphy AJ, Yancopoulos GD, Gromada J. Gusarova V, et al. Among authors: murphy aj. Cell. 2014 Oct 23;159(3):691-6. doi: 10.1016/j.cell.2014.09.027. Cell. 2014. PMID: 25417115 Free PMC article.
624 results