Paillusson S - Search Results

1

ER-mitochondria signaling regulates autophagy.

Gomez-Suaga P, Paillusson S, Miller CCJ. Gomez-Suaga P, et al. Among authors: paillusson s. Autophagy. 2017 Jul 3;13(7):1250-1251. doi: 10.1080/15548627.2017.1317913. Epub 2017 May 26. Autophagy. 2017. PMID: 28548902 Free PMC article.

2

The VAPB-PTPIP51 endoplasmic reticulum-mitochondria tethering proteins are present in neuronal synapses and regulate synaptic activity.

Gómez-Suaga P, Pérez-Nievas BG, Glennon EB, Lau DHW, Paillusson S, Mórotz GM, Calì T, Pizzo P, Noble W, Miller CCJ. Gómez-Suaga P, et al. Among authors: paillusson s. Acta Neuropathol Commun. 2019 Mar 6;7(1):35. doi: 10.1186/s40478-019-0688-4. Acta Neuropathol Commun. 2019. PMID: 30841933 Free PMC article.

3

Disruption of endoplasmic reticulum-mitochondria tethering proteins in post-mortem Alzheimer's disease brain.

Lau DHW, Paillusson S, Hartopp N, Rupawala H, Mórotz GM, Gomez-Suaga P, Greig J, Troakes C, Noble W, Miller CCJ. Lau DHW, et al. Among authors: paillusson s. Neurobiol Dis. 2020 Sep;143:105020. doi: 10.1016/j.nbd.2020.105020. Epub 2020 Jul 17. Neurobiol Dis. 2020. PMID: 32682953 Free PMC article.

4

ER-mitochondria associations are regulated by the VAPB-PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43.

Stoica R, De Vos KJ, Paillusson S, Mueller S, Sancho RM, Lau KF, Vizcay-Barrena G, Lin WL, Xu YF, Lewis J, Dickson DW, Petrucelli L, Mitchell JC, Shaw CE, Miller CC. Stoica R, et al. Among authors: paillusson s. Nat Commun. 2014 Jun 3;5:3996. doi: 10.1038/ncomms4996. Nat Commun. 2014. PMID: 24893131 Free PMC article.

5

There's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative Diseases.

Paillusson S, Stoica R, Gomez-Suaga P, Lau DHW, Mueller S, Miller T, Miller CCJ. Paillusson S, et al. Trends Neurosci. 2016 Mar;39(3):146-157. doi: 10.1016/j.tins.2016.01.008. Epub 2016 Feb 15. Trends Neurosci. 2016. PMID: 26899735 Free PMC article. Review.

6

ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.

Stoica R, Paillusson S, Gomez-Suaga P, Mitchell JC, Lau DH, Gray EH, Sancho RM, Vizcay-Barrena G, De Vos KJ, Shaw CE, Hanger DP, Noble W, Miller CC. Stoica R, et al. Among authors: paillusson s. EMBO Rep. 2016 Sep;17(9):1326-42. doi: 10.15252/embr.201541726. Epub 2016 Jul 14. EMBO Rep. 2016. PMID: 27418313 Free PMC article.

7

The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy.

Gomez-Suaga P, Paillusson S, Stoica R, Noble W, Hanger DP, Miller CCJ. Gomez-Suaga P, et al. Among authors: paillusson s. Curr Biol. 2017 Feb 6;27(3):371-385. doi: 10.1016/j.cub.2016.12.038. Epub 2017 Jan 26. Curr Biol. 2017. PMID: 28132811 Free PMC article.

8

α-Synuclein binds to the ER-mitochondria tethering protein VAPB to disrupt Ca²⁺ homeostasis and mitochondrial ATP production.

Paillusson S, Gomez-Suaga P, Stoica R, Little D, Gissen P, Devine MJ, Noble W, Hanger DP, Miller CCJ. Paillusson S, et al. Acta Neuropathol. 2017 Jul;134(1):129-149. doi: 10.1007/s00401-017-1704-z. Epub 2017 Mar 23. Acta Neuropathol. 2017. PMID: 28337542 Free PMC article.

9

Disruption of ER-mitochondria signalling in fronto-temporal dementia and related amyotrophic lateral sclerosis.

Lau DHW, Hartopp N, Welsh NJ, Mueller S, Glennon EB, Mórotz GM, Annibali A, Gomez-Suaga P, Stoica R, Paillusson S, Miller CCJ. Lau DHW, et al. Among authors: paillusson s. Cell Death Dis. 2018 Feb 28;9(3):327. doi: 10.1038/s41419-017-0022-7. Cell Death Dis. 2018. PMID: 29491392 Free PMC article. Review.

10

The PTPIP51 coiled-coil domain is important in VAPB binding, formation of ER-mitochondria contacts and IP3 receptor delivery of Ca²⁺ to mitochondria.

Mórotz GM, Martín-Guerrero SM, Markovinovic A, Paillusson S, Russell MRG, Machado PMP, Fleck RA, Noble W, Miller CCJ. Mórotz GM, et al. Among authors: paillusson s. Front Cell Dev Biol. 2022 Aug 31;10:920947. doi: 10.3389/fcell.2022.920947. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36120587 Free PMC article.

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