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Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure.
J Med Chem. 2017 Jun 22;60(12):5146-5161. doi: 10.1021/acs.jmedchem.7b00449. Epub 2017 Jun 12.
J Med Chem. 2017.
PMID: 28557445
Free article.
Nitric Oxide-Independent Soluble Guanylate Cyclase Activation Improves Vascular Function and Cardiac Remodeling in Sickle Cell Disease.
Potoka KP, Wood KC, Baust JJ, Bueno M, Hahn SA, Vanderpool RR, Bachman T, Mallampalli GM, Osei-Hwedieh DO, Schrott V, Sun B, Bullock GC, Becker-Pelster EM, Wittwer M, Stampfuss J, Mathar I, Stasch JP, Truebel H, Sandner P, Mora AL, Straub AC, Gladwin MT.
Potoka KP, et al. Among authors: becker pelster em.
Am J Respir Cell Mol Biol. 2018 May;58(5):636-647. doi: 10.1165/rcmb.2017-0292OC.
Am J Respir Cell Mol Biol. 2018.
PMID: 29268036
Free PMC article.
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Discovery and development of sGC stimulators for the treatment of pulmonary hypertension and rare diseases.
Sandner P, Becker-Pelster EM, Stasch JP.
Sandner P, et al. Among authors: becker pelster em.
Nitric Oxide. 2018 Jul 1;77:88-95. doi: 10.1016/j.niox.2018.05.001. Epub 2018 May 5.
Nitric Oxide. 2018.
PMID: 29738821
Review.
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Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
Hahn MG, Lampe T, El Sheikh S, Griebenow N, Woltering E, Schlemmer KH, Dietz L, Gerisch M, Wunder F, Becker-Pelster EM, Mondritzki T, Tinel H, Knorr A, Kern A, Lang D, Hueser J, Schomber T, Benardeau A, Eitner F, Truebel H, Mittendorf J, Kumar V, van den Akker F, Schaefer M, Geiss V, Sandner P, Stasch JP.
Hahn MG, et al. Among authors: becker pelster em.
J Med Chem. 2021 May 13;64(9):5323-5344. doi: 10.1021/acs.jmedchem.0c02154. Epub 2021 Apr 19.
J Med Chem. 2021.
PMID: 33872507
Free article.
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Identification and characterization of the new generation soluble guanylate cyclase stimulator BAY-747 designed for the treatment of resistant hypertension.
Wunder F, Stasch JP, Knorr A, Mondritzki T, Brockschnieder D, Becker-Pelster EM, Sandner P, Tinel H, Redlich G, Hartung IV, Vakalopoulos A, Follmann M.
Wunder F, et al. Among authors: becker pelster em.
Br J Pharmacol. 2023 Oct;180(19):2500-2513. doi: 10.1111/bph.16142. Epub 2023 Jun 20.
Br J Pharmacol. 2023.
PMID: 37170767
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Inhaled sGC Modulator Can Lower PH in Patients With COPD Without Deteriorating Oxygenation.
Saffaran S, Wang W, Das A, Schmitt W, Becker-Pelster EM, Hardman JG, Weimann G, Bates DG.
Saffaran S, et al. Among authors: becker pelster em.
CPT Pharmacometrics Syst Pharmacol. 2018 Aug;7(8):491-498. doi: 10.1002/psp4.12308. Epub 2018 Jul 2.
CPT Pharmacometrics Syst Pharmacol. 2018.
PMID: 29962065
Free PMC article.
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Exploring polyvinylpyrrolidone in the engineering of large porous PLGA microparticles via single emulsion method with tunable sustained release in the lung: In vitro and in vivo characterization.
Ni R, Muenster U, Zhao J, Zhang L, Becker-Pelster EM, Rosenbruch M, Mao S.
Ni R, et al. Among authors: becker pelster em.
J Control Release. 2017 Mar 10;249:11-22. doi: 10.1016/j.jconrel.2017.01.023. Epub 2017 Jan 18.
J Control Release. 2017.
PMID: 28109773
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Inhaled mosliciguat (BAY 1237592): targeting pulmonary vasculature via activating apo-sGC.
Becker-Pelster EM, Hahn MG, Delbeck M, Dietz L, Hüser J, Kopf J, Kraemer T, Marquardt T, Mondritzki T, Nagelschmitz J, Nikkho SM, Pires PV, Tinel H, Weimann G, Wunder F, Sandner P, Schuhmacher J, Stasch JP, Truebel HKF.
Becker-Pelster EM, et al.
Respir Res. 2022 Oct 1;23(1):272. doi: 10.1186/s12931-022-02189-1.
Respir Res. 2022.
PMID: 36183104
Free PMC article.
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