Huang S - Search Results

1

Genetic-Variation-Driven Gene-Expression Changes Highlight Genes with Important Functions for Kidney Disease.

Ko YA, Yi H, Qiu C, Huang S, Park J, Ledo N, Köttgen A, Li H, Rader DJ, Pack MA, Brown CD, Susztak K. Ko YA, et al. Among authors: huang s. Am J Hum Genet. 2017 Jun 1;100(6):940-953. doi: 10.1016/j.ajhg.2017.05.004. Am J Hum Genet. 2017. PMID: 28575649 Free PMC article.

2

Renal compartment-specific genetic variation analyses identify new pathways in chronic kidney disease.

Qiu C, Huang S, Park J, Park Y, Ko YA, Seasock MJ, Bryer JS, Xu XX, Song WC, Palmer M, Hill J, Guarnieri P, Hawkins J, Boustany-Kari CM, Pullen SS, Brown CD, Susztak K. Qiu C, et al. Among authors: huang s. Nat Med. 2018 Nov;24(11):1721-1731. doi: 10.1038/s41591-018-0194-4. Epub 2018 Oct 1. Nat Med. 2018. PMID: 30275566 Free PMC article.

3

Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity.

Gu X, Yang H, Sheng X, Ko YA, Qiu C, Park J, Huang S, Kember R, Judy RL, Park J, Damrauer SM, Nadkarni G, Loos RJF, My VTH, Chaudhary K, Bottinger EP, Paranjpe I, Saha A, Brown C, Akilesh S, Hung AM, Palmer M, Baras A, Overton JD, Reid J, Ritchie M, Rader DJ, Susztak K. Gu X, et al. Among authors: huang s. Sci Transl Med. 2021 Jan 13;13(576):eaaz1458. doi: 10.1126/scitranslmed.aaz1458. Sci Transl Med. 2021. PMID: 33441424 Free PMC article.

4

Epithelial Plasticity versus EMT in Kidney Fibrosis.

Huang S, Susztak K. Huang S, et al. Trends Mol Med. 2016 Jan;22(1):4-6. doi: 10.1016/j.molmed.2015.11.009. Epub 2015 Dec 11. Trends Mol Med. 2016. PMID: 26700490 Free PMC article.

5

Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease.

Park J, Shrestha R, Qiu C, Kondo A, Huang S, Werth M, Li M, Barasch J, Suszták K. Park J, et al. Among authors: huang s. Science. 2018 May 18;360(6390):758-763. doi: 10.1126/science.aar2131. Epub 2018 Apr 5. Science. 2018. PMID: 29622724 Free PMC article.

6

Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming.

Huang S, Park J, Qiu C, Chung KW, Li SY, Sirin Y, Han SH, Taylor V, Zimber-Strobl U, Susztak K. Huang S, et al. PLoS Biol. 2018 Sep 18;16(9):e2005233. doi: 10.1371/journal.pbio.2005233. eCollection 2018 Sep. PLoS Biol. 2018. PMID: 30226866 Free PMC article.

7

Genome-wide association studies identify the role of caspase-9 in kidney disease.

Doke T, Huang S, Qiu C, Sheng X, Seasock M, Liu H, Ma Z, Palmer M, Susztak K. Doke T, et al. Among authors: huang s. Sci Adv. 2021 Nov 5;7(45):eabi8051. doi: 10.1126/sciadv.abi8051. Epub 2021 Nov 5. Sci Adv. 2021. PMID: 34739325 Free PMC article.

8

Transcriptome-wide association analysis identifies DACH1 as a kidney disease risk gene that contributes to fibrosis.

Doke T, Huang S, Qiu C, Liu H, Guan Y, Hu H, Ma Z, Wu J, Miao Z, Sheng X, Zhou J, Cao A, Li J, Kaufman L, Hung A, Brown CD, Pestell R, Susztak K. Doke T, et al. Among authors: huang s. J Clin Invest. 2021 May 17;131(10):e141801. doi: 10.1172/JCI141801. J Clin Invest. 2021. PMID: 33998598 Free PMC article.

9

Sox9-Positive Progenitor Cells Play a Key Role in Renal Tubule Epithelial Regeneration in Mice.

Kang HM, Huang S, Reidy K, Han SH, Chinga F, Susztak K. Kang HM, et al. Among authors: huang s. Cell Rep. 2016 Feb 2;14(4):861-871. doi: 10.1016/j.celrep.2015.12.071. Epub 2016 Jan 14. Cell Rep. 2016. PMID: 26776520 Free PMC article.

10

Notch Pathway Is Activated via Genetic and Epigenetic Alterations and Is a Therapeutic Target in Clear Cell Renal Cancer.

Bhagat TD, Zou Y, Huang S, Park J, Palmer MB, Hu C, Li W, Shenoy N, Giricz O, Choudhary G, Yu Y, Ko YA, Izquierdo MC, Park AS, Vallumsetla N, Laurence R, Lopez R, Suzuki M, Pullman J, Kaner J, Gartrell B, Hakimi AA, Greally JM, Patel B, Benhadji K, Pradhan K, Verma A, Susztak K. Bhagat TD, et al. Among authors: huang s. J Biol Chem. 2017 Jan 20;292(3):837-846. doi: 10.1074/jbc.M116.745208. Epub 2016 Dec 1. J Biol Chem. 2017. PMID: 27909050 Free PMC article.

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