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WNT10A mutation causes ectodermal dysplasia by impairing progenitor cell proliferation and KLF4-mediated differentiation.
Xu M, Horrell J, Snitow M, Cui J, Gochnauer H, Syrett CM, Kallish S, Seykora JT, Liu F, Gaillard D, Katz JP, Kaestner KH, Levin B, Mansfield C, Douglas JE, Cowart BJ, Tordoff M, Liu F, Zhu X, Barlow LA, Rubin AI, McGrath JA, Morrisey EE, Chu EY, Millar SE. Xu M, et al. Among authors: tordoff m. Nat Commun. 2017 Jun 7;8:15397. doi: 10.1038/ncomms15397. Nat Commun. 2017. PMID: 28589954 Free PMC article.
CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes.
Taruno A, Vingtdeux V, Ohmoto M, Ma Z, Dvoryanchikov G, Li A, Adrien L, Zhao H, Leung S, Abernethy M, Koppel J, Davies P, Civan MM, Chaudhari N, Matsumoto I, Hellekant G, Tordoff MG, Marambaud P, Foskett JK. Taruno A, et al. Among authors: tordoff mg. Nature. 2013 Mar 14;495(7440):223-6. doi: 10.1038/nature11906. Epub 2013 Mar 6. Nature. 2013. PMID: 23467090 Free PMC article.
Salty taste deficits in CALHM1 knockout mice.
Tordoff MG, Ellis HT, Aleman TR, Downing A, Marambaud P, Foskett JK, Dana RM, McCaughey SA. Tordoff MG, et al. Chem Senses. 2014 Jul;39(6):515-28. doi: 10.1093/chemse/bju020. Epub 2014 May 20. Chem Senses. 2014. PMID: 24846212 Free PMC article.
Normal Taste Acceptance and Preference of PANX1 Knockout Mice.
Tordoff MG, Aleman TR, Ellis HT, Ohmoto M, Matsumoto I, Shestopalov VI, Mitchell CH, Foskett JK, Poole RL. Tordoff MG, et al. Chem Senses. 2015 Sep;40(7):453-9. doi: 10.1093/chemse/bjv025. Epub 2015 May 18. Chem Senses. 2015. PMID: 25987548 Free PMC article.
ERK1/2 activation in human taste bud cells regulates fatty acid signaling and gustatory perception of fat in mice and humans.
Subramaniam S, Ozdener MH, Abdoul-Azize S, Saito K, Malik B, Maquart G, Hashimoto T, Marambaud P, Aribi M, Tordoff MG, Besnard P, Khan NA. Subramaniam S, et al. Among authors: tordoff mg. FASEB J. 2016 Oct;30(10):3489-3500. doi: 10.1096/fj.201600422R. Epub 2016 Jun 29. FASEB J. 2016. PMID: 27358389 Free PMC article.
Our data demonstrate that ERK1/2-MAPK cascade is regulated by the opening of CALHM1 Ca(2+) channel in TBCs to modulate orogustatory detection of dietary lipids in mice and humans.-Subramaniam, S., Ozdener, M. H., Abdoul-Azize, S., Saito, K., Malik, B., Maquart, G., Hashimo …
Our data demonstrate that ERK1/2-MAPK cascade is regulated by the opening of CALHM1 Ca(2+) channel in TBCs to modulate orogustatory detectio …
CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes.
Ma Z, Taruno A, Ohmoto M, Jyotaki M, Lim JC, Miyazaki H, Niisato N, Marunaka Y, Lee RJ, Hoff H, Payne R, Demuro A, Parker I, Mitchell CH, Henao-Mejia J, Tanis JE, Matsumoto I, Tordoff MG, Foskett JK. Ma Z, et al. Among authors: tordoff mg. Neuron. 2018 May 2;98(3):547-561.e10. doi: 10.1016/j.neuron.2018.03.043. Epub 2018 Apr 19. Neuron. 2018. PMID: 29681531 Free PMC article.
Involvement of T1R3 in calcium-magnesium taste.
Tordoff MG, Shao H, Alarcón LK, Margolskee RF, Mosinger B, Bachmanov AA, Reed DR, McCaughey S. Tordoff MG, et al. Physiol Genomics. 2008 Aug 15;34(3):338-48. doi: 10.1152/physiolgenomics.90200.2008. Epub 2008 Jul 1. Physiol Genomics. 2008. PMID: 18593862 Free PMC article.
T1R3: a human calcium taste receptor.
Tordoff MG, Alarcón LK, Valmeki S, Jiang P. Tordoff MG, et al. Sci Rep. 2012;2:496. doi: 10.1038/srep00496. Epub 2012 Jul 6. Sci Rep. 2012. PMID: 22773945 Free PMC article.
168 results