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ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
Kocan M, Sarwar M, Ang SY, Xiao J, Marugan JJ, Hossain MA, Wang C, Hutchinson DS, Samuel CS, Agoulnik AI, Bathgate RAD, Summers RJ. Kocan M, et al. Among authors: bathgate rad. Sci Rep. 2017 Jun 7;7(1):2968. doi: 10.1038/s41598-017-02916-5. Sci Rep. 2017. PMID: 28592882 Free PMC article.
Relaxin-like bioactivity of ovine Insulin 3 (INSL3) analogues.
Claasz AA, Bond CP, Bathgate RA, Otvos L, Dawson NF, Summers RJ, Tregear GW, Wade JD. Claasz AA, et al. Eur J Biochem. 2002 Dec;269(24):6287-93. doi: 10.1046/j.1432-1033.2002.03348.x. Eur J Biochem. 2002. PMID: 12473125 Free article.
Relaxin: new peptides, receptors and novel actions.
Bathgate RA, Samuel CS, Burazin TC, Gundlach AL, Tregear GW. Bathgate RA, et al. Trends Endocrinol Metab. 2003 Jul;14(5):207-13. doi: 10.1016/s1043-2760(03)00081-x. Trends Endocrinol Metab. 2003. PMID: 12826326 Review.
Characterization of the mouse and rat relaxin receptors.
Scott DJ, Layfield S, Riesewijk A, Morita H, Tregear GW, Bathgate RA. Scott DJ, et al. Ann N Y Acad Sci. 2005 May;1041:8-12. doi: 10.1196/annals.1282.002. Ann N Y Acad Sci. 2005. PMID: 15956680
275 results