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ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.
Kocan M, Sarwar M, Ang SY, Xiao J, Marugan JJ, Hossain MA, Wang C, Hutchinson DS, Samuel CS, Agoulnik AI, Bathgate RAD, Summers RJ. Kocan M, et al. Among authors: samuel cs. Sci Rep. 2017 Jun 7;7(1):2968. doi: 10.1038/s41598-017-02916-5. Sci Rep. 2017. PMID: 28592882 Free PMC article.
Relaxin: new peptides, receptors and novel actions.
Bathgate RA, Samuel CS, Burazin TC, Gundlach AL, Tregear GW. Bathgate RA, et al. Among authors: samuel cs. Trends Endocrinol Metab. 2003 Jul;14(5):207-13. doi: 10.1016/s1043-2760(03)00081-x. Trends Endocrinol Metab. 2003. PMID: 12826326 Review.
189 results