Laptenko O - Search Results

1

Quantitative Analysis of the DNA Methylation Sensitivity of Transcription Factor Complexes.

Kribelbauer JF, Laptenko O, Chen S, Martini GD, Freed-Pastor WA, Prives C, Mann RS, Bussemaker HJ. Kribelbauer JF, et al. Among authors: laptenko o. Cell Rep. 2017 Jun 13;19(11):2383-2395. doi: 10.1016/j.celrep.2017.05.069. Cell Rep. 2017. PMID: 28614722 Free PMC article.

2

Accurate and sensitive quantification of protein-DNA binding affinity.

Rastogi C, Rube HT, Kribelbauer JF, Crocker J, Loker RE, Martini GD, Laptenko O, Freed-Pastor WA, Prives C, Stern DL, Mann RS, Bussemaker HJ. Rastogi C, et al. Among authors: laptenko o. Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3692-E3701. doi: 10.1073/pnas.1714376115. Epub 2018 Apr 2. Proc Natl Acad Sci U S A. 2018. PMID: 29610332 Free PMC article.

3

Anything but simple: a phosphorylation-driven toggle within Brd4 triggers gene-specific transcriptional activation.

Laptenko O, Prives C. Laptenko O, et al. Mol Cell. 2013 Mar 7;49(5):838-9. doi: 10.1016/j.molcel.2013.02.021. Mol Cell. 2013. PMID: 23473602 Free PMC article.

4

The p53 C terminus controls site-specific DNA binding and promotes structural changes within the central DNA binding domain.

Laptenko O, Shiff I, Freed-Pastor W, Zupnick A, Mattia M, Freulich E, Shamir I, Kadouri N, Kahan T, Manfredi J, Simon I, Prives C. Laptenko O, et al. Mol Cell. 2015 Mar 19;57(6):1034-1046. doi: 10.1016/j.molcel.2015.02.015. Mol Cell. 2015. PMID: 25794615 Free PMC article.

5

p53: master of life, death, and the epigenome.

Laptenko O, Prives C. Laptenko O, et al. Genes Dev. 2017 May 15;31(10):955-956. doi: 10.1101/gad.302364.117. Genes Dev. 2017. PMID: 28637690 Free PMC article. Review.

6

Transcriptional regulation by p53: one protein, many possibilities.

Laptenko O, Prives C. Laptenko O, et al. Cell Death Differ. 2006 Jun;13(6):951-61. doi: 10.1038/sj.cdd.4401916. Cell Death Differ. 2006. PMID: 16575405 Review.

7

p53 binding to nucleosomes within the p21 promoter in vivo leads to nucleosome loss and transcriptional activation.

Laptenko O, Beckerman R, Freulich E, Prives C. Laptenko O, et al. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10385-90. doi: 10.1073/pnas.1105680108. Epub 2011 May 23. Proc Natl Acad Sci U S A. 2011. PMID: 21606339 Free PMC article.

8

Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells.

Pfister NT, Fomin V, Regunath K, Zhou JY, Zhou W, Silwal-Pandit L, Freed-Pastor WA, Laptenko O, Neo SP, Bargonetti J, Hoque M, Tian B, Gunaratne J, Engebraaten O, Manley JL, Børresen-Dale AL, Neilsen PM, Prives C. Pfister NT, et al. Among authors: laptenko o. Genes Dev. 2015 Jun 15;29(12):1298-315. doi: 10.1101/gad.263202.115. Epub 2015 Jun 16. Genes Dev. 2015. PMID: 26080815 Free PMC article.

9

The Tail That Wags the Dog: How the Disordered C-Terminal Domain Controls the Transcriptional Activities of the p53 Tumor-Suppressor Protein.

Laptenko O, Tong DR, Manfredi J, Prives C. Laptenko O, et al. Trends Biochem Sci. 2016 Dec;41(12):1022-1034. doi: 10.1016/j.tibs.2016.08.011. Epub 2016 Sep 23. Trends Biochem Sci. 2016. PMID: 27669647 Free PMC article. Review.

10

Lysines in the tetramerization domain of p53 selectively modulate G1 arrest.

Beckerman R, Yoh K, Mattia-Sansobrino M, Zupnick A, Laptenko O, Karni-Schmidt O, Ahn J, Byeon IJ, Keezer S, Prives C. Beckerman R, et al. Among authors: laptenko o. Cell Cycle. 2016 Jun 2;15(11):1425-38. doi: 10.1080/15384101.2016.1170270. Epub 2016 May 21. Cell Cycle. 2016. PMID: 27210019 Free PMC article.

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