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Do COPD subtypes really exist? COPD heterogeneity and clustering in 10 independent cohorts.
Castaldi PJ, Benet M, Petersen H, Rafaels N, Finigan J, Paoletti M, Marike Boezen H, Vonk JM, Bowler R, Pistolesi M, Puhan MA, Anto J, Wauters E, Lambrechts D, Janssens W, Bigazzi F, Camiciottoli G, Cho MH, Hersh CP, Barnes K, Rennard S, Boorgula MP, Dy J, Hansel NN, Crapo JD, Tesfaigzi Y, Agusti A, Silverman EK, Garcia-Aymerich J. Castaldi PJ, et al. Among authors: lambrechts d. Thorax. 2017 Nov;72(11):998-1006. doi: 10.1136/thoraxjnl-2016-209846. Epub 2017 Jun 21. Thorax. 2017. PMID: 28637835 Free PMC article.
The 15q24/25 susceptibility variant for lung cancer and chronic obstructive pulmonary disease is associated with emphysema.
Lambrechts D, Buysschaert I, Zanen P, Coolen J, Lays N, Cuppens H, Groen HJ, Dewever W, van Klaveren RJ, Verschakelen J, Wijmenga C, Postma DS, Decramer M, Janssens W. Lambrechts D, et al. Am J Respir Crit Care Med. 2010 Mar 1;181(5):486-93. doi: 10.1164/rccm.200909-1364OC. Epub 2009 Dec 10. Am J Respir Crit Care Med. 2010. PMID: 20007924
Genomic copy number determines functional expression of {beta}-defensin 2 in airway epithelial cells and associates with chronic obstructive pulmonary disease.
Janssens W, Nuytten H, Dupont LJ, Van Eldere J, Vermeire S, Lambrechts D, Nackaerts K, Decramer M, Cassiman JJ, Cuppens H. Janssens W, et al. Among authors: lambrechts d. Am J Respir Crit Care Med. 2010 Jul 15;182(2):163-9. doi: 10.1164/rccm.200905-0767OC. Epub 2010 Apr 8. Am J Respir Crit Care Med. 2010. PMID: 20378733
Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report.
Silverman EK, Vestbo J, Agusti A, Anderson W, Bakke PS, Barnes KC, Barr RG, Bleecker ER, Boezen HM, Burkart KM, Celli BR, Cho MH, Cookson WO, Croxton T, Daley D, DeMeo DL, Gan W, Garcia-Aymerich J, Hall IP, Hansel NN, Hersh CP, Kalsheker N, Kiley JP, Kim WJ, Lambrechts D, Lee SD, Litonjua AA, Lomas DA, London SJ, Nishimura M, Nørdestgaard BG, O'Donnell CJ, Postma DS, Puhan MA, Tesfaigzi Y, Tobin MD, Vogelmeier C, Wilk JB, Wouters E, Young RP, Ziegler-Heitbrock L, MacNee W, Crapo JD. Silverman EK, et al. Among authors: lambrechts d. COPD. 2011 Apr;8(2):121-35. doi: 10.3109/15412555.2011.558864. COPD. 2011. PMID: 21495840 Free PMC article. No abstract available.
Variants in the 15q24/25 locus associate with lung function decline in active smokers.
Mohamed Hoesein FA, Wauters E, Janssens W, Groen HJ, Smolonska J, Wijmenga C, Postma DS, Boezen HM, De Jong PA, Decramer M, Lammers JW, Lambrechts D, Zanen P. Mohamed Hoesein FA, et al. Among authors: lambrechts d. PLoS One. 2013;8(1):e53219. doi: 10.1371/journal.pone.0053219. Epub 2013 Jan 18. PLoS One. 2013. PMID: 23349703 Free PMC article.
RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue.
Reynders K, Wauters E, Moisse M, Decaluwé H, De Leyn P, Peeters S, Lambrecht M, Nackaerts K, Dooms C, Janssens W, Vansteenkiste J, Lambrechts D, De Ruysscher D. Reynders K, et al. Among authors: lambrechts d. Radiat Oncol. 2018 Jul 17;13(1):131. doi: 10.1186/s13014-018-1075-1. Radiat Oncol. 2018. PMID: 30016964 Free PMC article.
604 results