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Page 1
The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability.
Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C, Blackwood D, McIntosh AM, Kirov G, Geschwind D, Murray RM, Di Forti M, Bramon E, Gandal M, Hultman CM, Sklar P; INTERVAL Study; UK10K Consortium; Palotie A, Sullivan PF, O'Donovan MC, Owen MJ, Barrett JC. Singh T, et al. Among authors: mcintosh am. Nat Genet. 2017 Aug;49(8):1167-1173. doi: 10.1038/ng.3903. Epub 2017 Jun 26. Nat Genet. 2017. PMID: 28650482 Free PMC article.
Modulation of hippocampal activation by genetic variation in the GRIK4 gene.
Whalley HC, Pickard BS, McIntosh AM, Zuliani R, Johnstone EC, Blackwood DH, Lawrie SM, Muir WJ, Hall J. Whalley HC, et al. Among authors: mcintosh am. Mol Psychiatry. 2009 May;14(5):465. doi: 10.1038/mp.2009.31. Mol Psychiatry. 2009. PMID: 19384317 No abstract available.
DISC1 in schizophrenia: genetic mouse models and human genomic imaging.
Johnstone M, Thomson PA, Hall J, McIntosh AM, Lawrie SM, Porteous DJ. Johnstone M, et al. Among authors: mcintosh am. Schizophr Bull. 2011 Jan;37(1):14-20. doi: 10.1093/schbul/sbq135. Epub 2010 Dec 13. Schizophr Bull. 2011. PMID: 21149852 Free PMC article. Review.
Genetic variants in the ErbB4 gene are associated with white matter integrity.
Zuliani R, Moorhead TW, Bastin ME, Johnstone EC, Lawrie SM, Brambilla P, O'Donovan MC, Owen MJ, Hall J, McIntosh AM. Zuliani R, et al. Among authors: mcintosh am. Psychiatry Res. 2011 Feb 28;191(2):133-7. doi: 10.1016/j.pscychresns.2010.11.001. Epub 2011 Jan 12. Psychiatry Res. 2011. PMID: 21232925 Free PMC article.
Effects of a mis-sense DISC1 variant on brain activation in two cohorts at high risk of bipolar disorder or schizophrenia.
Whalley HC, Sussmann JE, Johnstone M, Romaniuk L, Redpath H, Chakirova G, Mukherjee P, Hall J, Johnstone EC, Lawrie SM, McIntosh AM. Whalley HC, et al. Among authors: mcintosh am. Am J Med Genet B Neuropsychiatr Genet. 2012 Apr;159B(3):343-53. doi: 10.1002/ajmg.b.32035. Epub 2012 Feb 15. Am J Med Genet B Neuropsychiatr Genet. 2012. PMID: 22337479
Identification of common variants associated with human hippocampal and intracranial volumes.
Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christoforou A, Domin M, Grimm O, Hollinshead M, Holmes AJ, Homuth G, Hottenga JJ, Langan C, Lopez LM, Hansell NK, Hwang KS, Kim S, Laje G, Lee PH, Liu X, Loth E, Lourdusamy A, Mattingsdal M, Mohnke S, Maniega SM, Nho K, Nugent AC, O'Brien C, Papmeyer M, Pütz B, Ramasamy A, Rasmussen J, Rijpkema M, Risacher SL, Roddey JC, Rose EJ, Ryten M, Shen L, Sprooten E, Strengman E, Teumer A, Trabzuni D, Turner J, van Eijk K, van Erp TG, van Tol MJ, Wittfeld K, Wolf C, Woudstra S, Aleman A, Alhusaini S, Almasy L, Binder EB, Brohawn DG, Cantor RM, Carless MA, Corvin A, Czisch M, Curran JE, Davies G, de Almeida MA, Delanty N, Depondt C, Duggirala R, Dyer TD, Erk S, Fagerness J, Fox PT, Freimer NB, Gill M, Göring HH, Hagler DJ, Hoehn D, Holsboer F, Hoogman M, Hosten N, Jahanshad N, Johnson MP, Kasperaviciute D, Kent JW Jr, Kochunov P, Lancaster JL, Lawrie SM, Liewald DC, Mandl R, Matarin M, Mattheisen M, Meisenzahl E, Melle I, Moses EK, Mühleisen TW, Nauck M, Nöthen MM, Olvera RL, Pandolfo M, Pike GB, Puls R, Reinvang I, Rentería ME, Rietsc… See abstract for full author list ➔ Stein JL, et al. Among authors: mcintosh am. Nat Genet. 2012 Apr 15;44(5):552-61. doi: 10.1038/ng.2250. Nat Genet. 2012. PMID: 22504417 Free PMC article.
Anterior cingulate morphology in people at genetic high-risk of schizophrenia.
Meredith SM, Whyler NC, Stanfield AC, Chakirova G, Moorhead TW, Job DE, Giles S, McIntosh AM, Johnstone EC, Lawrie SM. Meredith SM, et al. Among authors: mcintosh am. Eur Psychiatry. 2012 Jul;27(5):377-85. doi: 10.1016/j.eurpsy.2011.11.004. Epub 2012 Apr 17. Eur Psychiatry. 2012. PMID: 22512930
A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins.
Eykelenboom JE, Briggs GJ, Bradshaw NJ, Soares DC, Ogawa F, Christie S, Malavasi EL, Makedonopoulou P, Mackie S, Malloy MP, Wear MA, Blackburn EA, Bramham J, McIntosh AM, Blackwood DH, Muir WJ, Porteous DJ, Millar JK. Eykelenboom JE, et al. Among authors: mcintosh am. Hum Mol Genet. 2012 Aug 1;21(15):3374-86. doi: 10.1093/hmg/dds169. Epub 2012 Apr 30. Hum Mol Genet. 2012. PMID: 22547224 Free PMC article.
553 results