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Neuroblastoma is composed of two super-enhancer-associated differentiation states.
van Groningen T, Koster J, Valentijn LJ, Zwijnenburg DA, Akogul N, Hasselt NE, Broekmans M, Haneveld F, Nowakowska NE, Bras J, van Noesel CJM, Jongejan A, van Kampen AH, Koster L, Baas F, van Dijk-Kerkhoven L, Huizer-Smit M, Lecca MC, Chan A, Lakeman A, Molenaar P, Volckmann R, Westerhout EM, Hamdi M, van Sluis PG, Ebus ME, Molenaar JJ, Tytgat GA, Westerman BA, van Nes J, Versteeg R. van Groningen T, et al. Among authors: jongejan a. Nat Genet. 2017 Aug;49(8):1261-1266. doi: 10.1038/ng.3899. Epub 2017 Jun 26. Nat Genet. 2017. PMID: 28650485
Liver X receptor alpha ensures blood-brain barrier function by suppressing SNAI2.
Vacondio D, Nogueira Pinto H, Coenen L, Mulder IA, Fontijn R, van Het Hof B, Fung WK, Jongejan A, Kooij G, Zelcer N, Rozemuller AJ, de Vries HE, de Wit NM. Vacondio D, et al. Among authors: jongejan a. Cell Death Dis. 2023 Nov 28;14(11):781. doi: 10.1038/s41419-023-06316-8. Cell Death Dis. 2023. PMID: 38016947 Free PMC article.
Tissue-specific inflammation and insulin sensitivity in subjects with obesity.
Oussaada SM, Kilicarslan M, de Weijer BA, Gilijamse PW, Şekercan A, Virtue S, Janssen IMC, van de Laar A, Demirkiran A, van Wagensveld BA, Houdijk APJ, Jongejan A, Moerland PD, Verheij J, Geijtenbeek TB, Bloks VW, de Goffau MC, Romijn JA, Nieuwdorp M, Vidal-Puig A, Ter Horst KW, Serlie MJ. Oussaada SM, et al. Among authors: jongejan a. Diabetes Res Clin Pract. 2024 May;211:111663. doi: 10.1016/j.diabres.2024.111663. Epub 2024 Apr 12. Diabetes Res Clin Pract. 2024. PMID: 38616042 Free article.
HDAC1/2 inhibitor therapy improves multiple organ systems in aged mice.
Tammaro A, Daniels EG, Hu IM, 't Hart KC, Reid K, Juni RP, Butter LM, Vasam G, Kamble R, Jongejan A, Aviv RI, Roelofs JJTH, Aronica E, Boon RA, Menzies KJ, Houtkooper RH, Janssens GE. Tammaro A, et al. Among authors: jongejan a. iScience. 2023 Dec 12;27(1):108681. doi: 10.1016/j.isci.2023.108681. eCollection 2024 Jan 19. iScience. 2023. PMID: 38269100 Free PMC article.
Anti-retroviral treatment with zidovudine alters pyrimidine metabolism, reduces translation, and extends healthy longevity via ATF-4.
McIntyre RL, Molenaars M, Schomakers BV, Gao AW, Kamble R, Jongejan A, van Weeghel M, van Kuilenburg ABP, Possemato R, Houtkooper RH, Janssens GE. McIntyre RL, et al. Among authors: jongejan a. Cell Rep. 2023 Jan 31;42(1):111928. doi: 10.1016/j.celrep.2022.111928. Epub 2022 Dec 30. Cell Rep. 2023. PMID: 36640360 Free article.
Mutations in ZBTB20 cause Primrose syndrome.
Cordeddu V, Redeker B, Stellacci E, Jongejan A, Fragale A, Bradley TE, Anselmi M, Ciolfi A, Cecchetti S, Muto V, Bernardini L, Azage M, Carvalho DR, Espay AJ, Male A, Molin AM, Posmyk R, Battisti C, Casertano A, Melis D, van Kampen A, Baas F, Mannens MM, Bocchinfuso G, Stella L, Tartaglia M, Hennekam RC. Cordeddu V, et al. Among authors: jongejan a. Nat Genet. 2014 Aug;46(8):815-7. doi: 10.1038/ng.3035. Epub 2014 Jul 13. Nat Genet. 2014. PMID: 25017102
121 results