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Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.
Miller TE, Liau BB, Wallace LC, Morton AR, Xie Q, Dixit D, Factor DC, Kim LJY, Morrow JJ, Wu Q, Mack SC, Hubert CG, Gillespie SM, Flavahan WA, Hoffmann T, Thummalapalli R, Hemann MT, Paddison PJ, Horbinski CM, Zuber J, Scacheri PC, Bernstein BE, Tesar PJ, Rich JN. Miller TE, et al. Among authors: hubert cg. Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5. Nature. 2017. PMID: 28678782 Free PMC article.
Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells.
Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, Olson JM, Paddison PJ. Ding Y, et al. Among authors: hubert cg. Cancer Discov. 2013 Feb;3(2):198-211. doi: 10.1158/2159-8290.CD-12-0353. Epub 2012 Nov 15. Cancer Discov. 2013. PMID: 23154965 Free PMC article.
CDC20 maintains tumor initiating cells.
Xie Q, Wu Q, Mack SC, Yang K, Kim L, Hubert CG, Flavahan WA, Chu C, Bao S, Rich JN. Xie Q, et al. Among authors: hubert cg. Oncotarget. 2015 May 30;6(15):13241-54. doi: 10.18632/oncotarget.3676. Oncotarget. 2015. PMID: 25938542 Free PMC article.
Differential connexin function enhances self-renewal in glioblastoma.
Hitomi M, Deleyrolle LP, Mulkearns-Hubert EE, Jarrar A, Li M, Sinyuk M, Otvos B, Brunet S, Flavahan WA, Hubert CG, Goan W, Hale JS, Alvarado AG, Zhang A, Rohaus M, Oli M, Vedam-Mai V, Fortin JM, Futch HS, Griffith B, Wu Q, Xia CH, Gong X, Ahluwalia MS, Rich JN, Reynolds BA, Lathia JD. Hitomi M, et al. Among authors: hubert cg. Cell Rep. 2015 May 19;11(7):1031-42. doi: 10.1016/j.celrep.2015.04.021. Epub 2015 May 7. Cell Rep. 2015. PMID: 25959821 Free PMC article.
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells.
Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. Schonberg DL, et al. Among authors: hubert cg. Cancer Cell. 2015 Oct 12;28(4):441-455. doi: 10.1016/j.ccell.2015.09.002. Cancer Cell. 2015. PMID: 26461092 Free PMC article.
An epigenetic gateway to brain tumor cell identity.
Mack SC, Hubert CG, Miller TE, Taylor MD, Rich JN. Mack SC, et al. Among authors: hubert cg. Nat Neurosci. 2016 Jan;19(1):10-9. doi: 10.1038/nn.4190. Nat Neurosci. 2016. PMID: 26713744 Free PMC article. Review.
Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events.
Ayuso JM, Monge R, Martínez-González A, Virumbrales-Muñoz M, Llamazares GA, Berganzo J, Hernández-Laín A, Santolaria J, Doblaré M, Hubert C, Rich JN, Sánchez-Gómez P, Pérez-García VM, Ochoa I, Fernández LJ. Ayuso JM, et al. Neuro Oncol. 2017 Apr 1;19(4):503-513. doi: 10.1093/neuonc/now230. Neuro Oncol. 2017. PMID: 28062831 Free PMC article.
39 results