Zhang J - Search Results

1

Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction.

Li Z, Brecher M, Deng YQ, Zhang J, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, Banavali N, Zhou J, Boles N, Xia M, Kramer LD, Qin CF, Li H. Li Z, et al. Among authors: zhang j, zhang nn. Cell Res. 2017 Aug;27(8):1046-1064. doi: 10.1038/cr.2017.88. Epub 2017 Jul 7. Cell Res. 2017. PMID: 28685770 Free PMC article.

2

Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase.

Brecher M, Chen H, Liu B, Banavali NK, Jones SA, Zhang J, Li Z, Kramer LD, Li H. Brecher M, et al. Among authors: zhang j. PLoS One. 2015 Jun 22;10(6):e0130062. doi: 10.1371/journal.pone.0130062. eCollection 2015. PLoS One. 2015. PMID: 26098995 Free PMC article.

3

A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease.

Brecher M, Li Z, Liu B, Zhang J, Koetzner CA, Alifarag A, Jones SA, Lin Q, Kramer LD, Li H. Brecher M, et al. Among authors: zhang j. PLoS Pathog. 2017 May 25;13(5):e1006411. doi: 10.1371/journal.ppat.1006411. eCollection 2017 May. PLoS Pathog. 2017. PMID: 28542603 Free PMC article.

4

Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease.

Li Z, Sakamuru S, Huang R, Brecher M, Koetzner CA, Zhang J, Chen H, Qin CF, Zhang QY, Zhou J, Kramer LD, Xia M, Li H. Li Z, et al. Among authors: zhang qy, zhang j. Antiviral Res. 2018 Feb;150:217-225. doi: 10.1016/j.antiviral.2017.12.018. Epub 2017 Dec 27. Antiviral Res. 2018. PMID: 29288700 Free PMC article.

5

JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both In Vitro and In Vivo.

Li Z, Xu J, Lang Y, Fan X, Kuo L, D'Brant L, Hu S, Samrat SK, Trudeau N, Tharappel AM, Rugenstein N, Koetzner CA, Zhang J, Chen H, Kramer LD, Butler D, Zhang QY, Zhou J, Li H. Li Z, et al. Among authors: zhang qy, zhang j. ACS Infect Dis. 2020 Oct 9;6(10):2616-2628. doi: 10.1021/acsinfecdis.0c00217. Epub 2020 Sep 21. ACS Infect Dis. 2020. PMID: 32866370 Free PMC article.

6

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.

Li Z, Lang Y, Sakamuru S, Samrat S, Trudeau N, Kuo L, Rugenstein N, Tharappel A, D'Brant L, Koetzner CA, Hu S, Zhang J, Huang R, Kramer LD, Butler D, Xia M, Li H. Li Z, et al. Among authors: zhang j. Emerg Microbes Infect. 2020 Dec;9(1):2404-2416. doi: 10.1080/22221751.2020.1838954. Emerg Microbes Infect. 2020. PMID: 33078696 Free PMC article.

7

The flavivirus protease as a target for drug discovery.

Brecher M, Zhang J, Li H. Brecher M, et al. Among authors: zhang j. Virol Sin. 2013 Dec;28(6):326-36. doi: 10.1007/s12250-013-3390-x. Epub 2013 Nov 14. Virol Sin. 2013. PMID: 24242363 Free PMC article. Review.

8

Identification and Characterization of Novel Broad-Spectrum Inhibitors of the Flavivirus Methyltransferase.

Brecher M, Chen H, Li Z, Banavali NK, Jones SA, Zhang J, Kramer LD, Li H. Brecher M, et al. Among authors: zhang j. ACS Infect Dis. 2015 Aug 14;1(8):340-9. doi: 10.1021/acsinfecdis.5b00070. Epub 2015 Jul 31. ACS Infect Dis. 2015. PMID: 26726314 Free PMC article.

9

Selective inhibition of the West Nile virus methyltransferase by nucleoside analogs.

Chen H, Liu L, Jones SA, Banavali N, Kass J, Li Z, Zhang J, Kramer LD, Ghosh AK, Li H. Chen H, et al. Among authors: zhang j. Antiviral Res. 2013 Mar;97(3):232-9. doi: 10.1016/j.antiviral.2012.12.012. Epub 2012 Dec 22. Antiviral Res. 2013. PMID: 23267828 Free PMC article.

10

S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase.

Chen H, Zhou B, Brecher M, Banavali N, Jones SA, Li Z, Zhang J, Nag D, Kramer LD, Ghosh AK, Li H. Chen H, et al. Among authors: zhang j. PLoS One. 2013 Oct 9;8(10):e76900. doi: 10.1371/journal.pone.0076900. eCollection 2013. PLoS One. 2013. PMID: 24130807 Free PMC article.

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