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Small molecule metalloprotease inhibitor with in vitro, ex vivo and in vivo efficacy against botulinum neurotoxin serotype A.
Jacobson AR, Adler M, Silvaggi NR, Allen KN, Smith GM, Fredenburg RA, Stein RL, Park JB, Feng X, Shoemaker CB, Deshpande SS, Goodnough MC, Malizio CJ, Johnson EA, Pellett S, Tepp WH, Tzipori S. Jacobson AR, et al. Among authors: goodnough mc. Toxicon. 2017 Oct;137:36-47. doi: 10.1016/j.toxicon.2017.06.016. Epub 2017 Jul 8. Toxicon. 2017. PMID: 28698055 Free PMC article.
An in vitro and in vivo disconnect uncovered through high-throughput identification of botulinum neurotoxin A antagonists.
Eubanks LM, Hixon MS, Jin W, Hong S, Clancy CM, Tepp WH, Baldwin MR, Malizio CJ, Goodnough MC, Barbieri JT, Johnson EA, Boger DL, Dickerson TJ, Janda KD. Eubanks LM, et al. Among authors: goodnough mc. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2602-7. doi: 10.1073/pnas.0611213104. Epub 2007 Feb 9. Proc Natl Acad Sci U S A. 2007. PMID: 17293454 Free PMC article.
Purification of Clostridium botulinum type A neurotoxin.
Malizio CJ, Goodnough MC, Johnson EA. Malizio CJ, et al. Among authors: goodnough mc. Methods Mol Biol. 2000;145:27-39. doi: 10.1385/1-59259-052-7:27. Methods Mol Biol. 2000. PMID: 10820714 No abstract available.
19 results