Lu Y - Search Results

1

LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formation.

Raab M, Lu Y, Kohler K, Smith X, Strebhardt K, Rudd CE. Raab M, et al. Among authors: lu y. Nat Commun. 2017 Jul 12;8:16001. doi: 10.1038/ncomms16001. Nat Commun. 2017. PMID: 28699640 Free PMC article.

2

Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion.

Wang H, Liu H, Lu Y, Lovatt M, Wei B, Rudd CE. Wang H, et al. Among authors: lu y. Mol Cell Biol. 2007 Oct;27(19):6863-75. doi: 10.1128/MCB.00556-07. Epub 2007 Jul 23. Mol Cell Biol. 2007. PMID: 17646386 Free PMC article.

3

T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes.

Raab M, Wang H, Lu Y, Smith X, Wu Z, Strebhardt K, Ladbury JE, Rudd CE. Raab M, et al. Among authors: lu y. Immunity. 2010 Apr 23;32(4):541-56. doi: 10.1016/j.immuni.2010.03.007. Epub 2010 Mar 25. Immunity. 2010. PMID: 20346707 Free PMC article.

4

Non-cleavable talin rescues defect in the T-cell conjugation of T-cells deficient in the immune adaptor SKAP1.

Lim D, Lu Y, Rudd CE. Lim D, et al. Among authors: lu y. Immunol Lett. 2016 Apr;172:40-6. doi: 10.1016/j.imlet.2016.02.004. Epub 2016 Feb 19. Immunol Lett. 2016. PMID: 26905930 Free PMC article.

5

SKAP1 is dispensable for chemokine-induced migration of primary T-cells.

Wang H, Lu Y, Rudd CE. Wang H, et al. Among authors: lu y. Immunol Lett. 2010 Feb 16;128(2):148-53. doi: 10.1016/j.imlet.2009.10.010. Epub 2009 Oct 31. Immunol Lett. 2010. PMID: 19883688 Free PMC article.

6

Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal.

Lu Y, Schneider H, Rudd CE. Lu Y, et al. Blood. 2012 Nov 29;120(23):4560-70. doi: 10.1182/blood-2012-04-421420. Epub 2012 Oct 9. Blood. 2012. PMID: 23047820 Free PMC article.

7

The chemokine CXCL12 generates costimulatory signals in T cells to enhance phosphorylation and clustering of the adaptor protein SLP-76.

Smith X, Schneider H, Köhler K, Liu H, Lu Y, Rudd CE. Smith X, et al. Among authors: lu y. Sci Signal. 2013 Jul 30;6(286):ra65. doi: 10.1126/scisignal.2004018. Sci Signal. 2013. PMID: 23901140

8

CD45 ligation expands Tregs by promoting interactions with DCs.

Camirand G, Wang Y, Lu Y, Wan YY, Lin Y, Deng S, Guz G, Perkins DL, Finn PW, Farber DL, Flavell RA, Shlomchik WD, Lakkis FG, Rudd CE, Rothstein DM. Camirand G, et al. Among authors: lu y. J Clin Invest. 2014 Oct;124(10):4603-13. doi: 10.1172/JCI74087. Epub 2014 Sep 9. J Clin Invest. 2014. PMID: 25202978 Free PMC article.

9

Impaired Autophagy in CD11b⁺ Dendritic Cells Expands CD4⁺ Regulatory T Cells and Limits Atherosclerosis in Mice.

Clement M, Raffort J, Lareyre F, Tsiantoulas D, Newland S, Lu Y, Masters L, Harrison J, Saveljeva S, Ma MKL, Ozsvar-Kozma M, Lam BYH, Yeo GSH, Binder CJ, Kaser A, Mallat Z. Clement M, et al. Among authors: lu y. Circ Res. 2019 Nov 8;125(11):1019-1034. doi: 10.1161/CIRCRESAHA.119.315248. Epub 2019 Oct 15. Circ Res. 2019. PMID: 31610723 Free PMC article.

10

Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet.

Nus M, Sage AP, Lu Y, Masters L, Lam BYH, Newland S, Weller S, Tsiantoulas D, Raffort J, Marcus D, Finigan A, Kitt L, Figg N, Schirmbeck R, Kneilling M, Yeo GSH, Binder CJ, de la Pompa JL, Mallat Z. Nus M, et al. Among authors: lu y. Nat Med. 2017 May;23(5):601-610. doi: 10.1038/nm.4315. Epub 2017 Apr 17. Nat Med. 2017. PMID: 28414328 Free article.

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