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Mutation intolerant genes and targets of FMRP are enriched for nonsynonymous alleles in schizophrenia.
Leonenko G, Richards AL, Walters JT, Pocklington A, Chambert K, Al Eissa MM, Sharp SI, O'Brien NL, Curtis D, Bass NJ, McQuillin A, Hultman C, Moran JL, McCarroll SA, Sklar P, Neale BM, Holmans PA, Owen MJ, Sullivan PF, O'Donovan MC. Leonenko G, et al. Am J Med Genet B Neuropsychiatr Genet. 2017 Oct;174(7):724-731. doi: 10.1002/ajmg.b.32560. Epub 2017 Jul 18. Am J Med Genet B Neuropsychiatr Genet. 2017. PMID: 28719003 Free PMC article.
No major schizophrenia locus detected on chromosome 1q in a large multicenter sample.
Levinson DF, Holmans PA, Laurent C, Riley B, Pulver AE, Gejman PV, Schwab SG, Williams NM, Owen MJ, Wildenauer DB, Sanders AR, Nestadt G, Mowry BJ, Wormley B, Bauché S, Soubigou S, Ribble R, Nertney DA, Liang KY, Martinolich L, Maier W, Norton N, Williams H, Albus M, Carpenter EB, DeMarchi N, Ewen-White KR, Walsh D, Jay M, Deleuze JF, O'Neill FA, Papadimitriou G, Weilbaecher A, Lerer B, O'Donovan MC, Dikeos D, Silverman JM, Kendler KS, Mallet J, Crowe RR, Walters M. Levinson DF, et al. Science. 2002 Apr 26;296(5568):739-41. doi: 10.1126/science.1069914. Science. 2002. PMID: 11976456
Sequence variation in the CHAT locus shows no association with late-onset Alzheimer's disease.
Harold D, Peirce T, Moskvina V, Myers A, Jones S, Hollingworth P, Moore P, Lovestone S, Powell J, Foy C, Archer N, Walter S, Edmonson A, McIlroy S, Craig D, Passmore PA, Goate A, Hardy J, O'Donovan M, Williams J, Liddell M, Owen MJ, Jones L. Harold D, et al. Hum Genet. 2003 Aug;113(3):258-67. doi: 10.1007/s00439-003-0960-2. Epub 2003 May 21. Hum Genet. 2003. PMID: 12759818
635 results