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RNA Misprocessing in C9orf72-Linked Neurodegeneration.
Barker HV, Niblock M, Lee YB, Shaw CE, Gallo JM. Barker HV, et al. Among authors: gallo jm. Front Cell Neurosci. 2017 Jul 11;11:195. doi: 10.3389/fncel.2017.00195. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28744202 Free PMC article. Review.
A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-α mediates C9orf72-related neurodegeneration.
Solomon DA, Stepto A, Au WH, Adachi Y, Diaper DC, Hall R, Rekhi A, Boudi A, Tziortzouda P, Lee YB, Smith B, Bridi JC, Spinelli G, Dearlove J, Humphrey DM, Gallo JM, Troakes C, Fanto M, Soller M, Rogelj B, Parsons RB, Shaw CE, Hortobágyi T, Hirth F. Solomon DA, et al. Among authors: gallo jm. Brain. 2018 Oct 1;141(10):2908-2924. doi: 10.1093/brain/awy241. Brain. 2018. PMID: 30239641 Free PMC article.
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Lee YB, Baskaran P, Gomez-Deza J, Chen HJ, Nishimura AL, Smith BN, Troakes C, Adachi Y, Stepto A, Petrucelli L, Gallo JM, Hirth F, Rogelj B, Guthrie S, Shaw CE. Lee YB, et al. Among authors: gallo jm. Hum Mol Genet. 2021 Apr 26;30(3-4):318-320. doi: 10.1093/hmg/ddaa181. Hum Mol Genet. 2021. PMID: 32888026 Free PMC article. No abstract available.
Cytoplasmic TDP-43 is involved in cell fate during stress recovery.
Lee YB, Scotter EL, Lee DY, Troakes C, Mitchell J, Rogelj B, Gallo JM, Shaw CE. Lee YB, et al. Among authors: gallo jm. Hum Mol Genet. 2021 Dec 27;31(2):166-175. doi: 10.1093/hmg/ddab227. Hum Mol Genet. 2021. PMID: 34378050 Free PMC article.
238 results