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NFIA co-localizes with PPARγ and transcriptionally controls the brown fat gene program.
Hiraike Y, Waki H, Yu J, Nakamura M, Miyake K, Nagano G, Nakaki R, Suzuki K, Kobayashi H, Yamamoto S, Sun W, Aoyama T, Hirota Y, Ohno H, Oki K, Yoneda M, White AP, Tseng YH, Cypess AM, Larsen TJ, Jespersen NZ, Scheele C, Tsutsumi S, Aburatani H, Yamauchi T, Kadowaki T. Hiraike Y, et al. Among authors: cypess am. Nat Cell Biol. 2017 Sep;19(9):1081-1092. doi: 10.1038/ncb3590. Epub 2017 Aug 14. Nat Cell Biol. 2017. PMID: 28812581 Free PMC article.
Identification and importance of brown adipose tissue in adult humans.
Cypess AM, Lehman S, Williams G, Tal I, Rodman D, Goldfine AB, Kuo FC, Palmer EL, Tseng YH, Doria A, Kolodny GM, Kahn CR. Cypess AM, et al. N Engl J Med. 2009 Apr 9;360(15):1509-17. doi: 10.1056/NEJMoa0810780. N Engl J Med. 2009. PMID: 19357406 Free PMC article.
Cellular bioenergetics as a target for obesity therapy.
Tseng YH, Cypess AM, Kahn CR. Tseng YH, et al. Among authors: cypess am. Nat Rev Drug Discov. 2010 Jun;9(6):465-82. doi: 10.1038/nrd3138. Nat Rev Drug Discov. 2010. PMID: 20514071 Free PMC article. Review.
Anatomical localization, gene expression profiling and functional characterization of adult human neck brown fat.
Cypess AM, White AP, Vernochet C, Schulz TJ, Xue R, Sass CA, Huang TL, Roberts-Toler C, Weiner LS, Sze C, Chacko AT, Deschamps LN, Herder LM, Truchan N, Glasgow AL, Holman AR, Gavrila A, Hasselgren PO, Mori MA, Molla M, Tseng YH. Cypess AM, et al. Nat Med. 2013 May;19(5):635-9. doi: 10.1038/nm.3112. Epub 2013 Apr 21. Nat Med. 2013. PMID: 23603815 Free PMC article.
IRF4 is a key thermogenic transcriptional partner of PGC-1α.
Kong X, Banks A, Liu T, Kazak L, Rao RR, Cohen P, Wang X, Yu S, Lo JC, Tseng YH, Cypess AM, Xue R, Kleiner S, Kang S, Spiegelman BM, Rosen ED. Kong X, et al. Among authors: cypess am. Cell. 2014 Jul 3;158(1):69-83. doi: 10.1016/j.cell.2014.04.049. Cell. 2014. PMID: 24995979 Free PMC article.
ASC-1, PAT2, and P2RX5 are cell surface markers for white, beige, and brown adipocytes.
Ussar S, Lee KY, Dankel SN, Boucher J, Haering MF, Kleinridders A, Thomou T, Xue R, Macotela Y, Cypess AM, Tseng YH, Mellgren G, Kahn CR. Ussar S, et al. Among authors: cypess am. Sci Transl Med. 2014 Jul 30;6(247):247ra103. doi: 10.1126/scitranslmed.3008490. Sci Transl Med. 2014. PMID: 25080478 Free PMC article.
91 results