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Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain.
J Heterocycl Chem. 2017 Mar;54(2):1228-1235. doi: 10.1002/jhet.2696. Epub 2016 Jun 1.
J Heterocycl Chem. 2017.
PMID: 28819330
Free PMC article.
Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential.
Sandweiss AJ, McIntosh MI, Moutal A, Davidson-Knapp R, Hu J, Giri AK, Yamamoto T, Hruby VJ, Khanna R, Largent-Milnes TM, Vanderah TW.
Sandweiss AJ, et al. Among authors: mcintosh mi.
Mol Psychiatry. 2018 Aug;23(8):1745-1755. doi: 10.1038/mp.2017.102. Epub 2017 May 9.
Mol Psychiatry. 2018.
PMID: 28485408
Free PMC article.
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Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the κ Opioid Receptor.
Ramos-Colon CN, Lee YS, Remesic M, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM, Vanderah TW, Streicher J, Porreca F, Hruby VJ.
Ramos-Colon CN, et al. Among authors: mcintosh mi.
J Med Chem. 2016 Nov 23;59(22):10291-10298. doi: 10.1021/acs.jmedchem.6b01411. Epub 2016 Nov 8.
J Med Chem. 2016.
PMID: 27797517
Free PMC article.
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17-β-Estradiol induces spreading depression and pain behavior in alert female rats.
Sandweiss AJ, Cottier KE, McIntosh MI, Dussor G, Davis TP, Vanderah TW, Largent-Milnes TM.
Sandweiss AJ, et al. Among authors: mcintosh mi.
Oncotarget. 2017 Dec 9;8(69):114109-114122. doi: 10.18632/oncotarget.23141. eCollection 2017 Dec 26.
Oncotarget. 2017.
PMID: 29371973
Free PMC article.
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A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.
Edwards KA, Havelin JJ, Mcintosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM.
Edwards KA, et al. Among authors: mcintosh mi.
J Pain. 2018 Jun;19(6):612-625. doi: 10.1016/j.jpain.2018.01.002. Epub 2018 Jan 31.
J Pain. 2018.
PMID: 29371114
Free article.
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