Deora GS - Search Results

1

Multifunctional Analogs of Kynurenic Acid for the Treatment of Alzheimer's Disease: Synthesis, Pharmacology, and Molecular Modeling Studies.

Deora GS, Kantham S, Chan S, Dighe SN, Veliyath SK, McColl G, Parat MO, McGeary RP, Ross BP. Deora GS, et al. ACS Chem Neurosci. 2017 Dec 20;8(12):2667-2675. doi: 10.1021/acschemneuro.7b00229. Epub 2017 Sep 8. ACS Chem Neurosci. 2017. PMID: 28825789

2

Effect of the Biphenyl Neolignan Honokiol on Aβ₄₂-Induced Toxicity in Caenorhabditis elegans, Aβ₄₂ Fibrillation, Cholinesterase Activity, DPPH Radicals, and Iron(II) Chelation.

Kantham S, Chan S, McColl G, Miles JA, Veliyath SK, Deora GS, Dighe SN, Khabbazi S, Parat MO, Ross BP. Kantham S, et al. Among authors: deora gs. ACS Chem Neurosci. 2017 Sep 20;8(9):1901-1912. doi: 10.1021/acschemneuro.7b00071. Epub 2017 Jul 19. ACS Chem Neurosci. 2017. PMID: 28650631

3

Rapid discovery of a selective butyrylcholinesterase inhibitor using structure-based virtual screening.

Miles JA, Kapure JS, Deora GS, Courageux C, Igert A, Dias J, McGeary RP, Brazzolotto X, Ross BP. Miles JA, et al. Among authors: deora gs. Bioorg Med Chem Lett. 2020 Dec 15;30(24):127609. doi: 10.1016/j.bmcl.2020.127609. Epub 2020 Oct 8. Bioorg Med Chem Lett. 2020. PMID: 33039562

4

Discovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual Screening.

Dighe SN, Deora GS, De la Mora E, Nachon F, Chan S, Parat MO, Brazzolotto X, Ross BP. Dighe SN, et al. Among authors: deora gs. J Med Chem. 2016 Aug 25;59(16):7683-9. doi: 10.1021/acs.jmedchem.6b00356. Epub 2016 Jul 26. J Med Chem. 2016. PMID: 27405689

5

A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites.

Zhang S, Sakuma M, Deora GS, Levy CW, Klausing A, Breda C, Read KD, Edlin CD, Ross BP, Wright Muelas M, Day PJ, O'Hagan S, Kell DB, Schwarcz R, Leys D, Heyes DJ, Giorgini F, Scrutton NS. Zhang S, et al. Among authors: deora gs. Commun Biol. 2019 Jul 24;2:271. doi: 10.1038/s42003-019-0520-5. eCollection 2019. Commun Biol. 2019. PMID: 31372510 Free PMC article.

6

Synthesis of novel benzimidazole acrylonitriles for inhibition of Plasmodium falciparum growth by dual target inhibition.

Sharma K, Shrivastava A, Mehra RN, Deora GS, Alam MM, Zaman MS, Akhter M. Sharma K, et al. Among authors: deora gs. Arch Pharm (Weinheim). 2018 Jan;351(1). doi: 10.1002/ardp.201700251. Epub 2017 Dec 11. Arch Pharm (Weinheim). 2018. PMID: 29227011

7

Expansion of a novel lead targeting M. tuberculosis DHFR as antitubercular agents.

Sharma K, Tanwar O, Deora GS, Ali S, Alam MM, Zaman MS, Krishna VS, Sriram D, Akhter M. Sharma K, et al. Among authors: deora gs. Bioorg Med Chem. 2019 Apr 1;27(7):1421-1429. doi: 10.1016/j.bmc.2019.02.053. Epub 2019 Feb 26. Bioorg Med Chem. 2019. PMID: 30827867

8

Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons.

Jogula S, Soorneedi AR, Gaddam J, Chamakuri S, Deora GS, Indarapu RK, Ramgopal MK, Dravida S, Arya P. Jogula S, et al. Among authors: deora gs. Eur J Med Chem. 2017 Jul 28;135:110-116. doi: 10.1016/j.ejmech.2017.03.082. Epub 2017 Apr 18. Eur J Med Chem. 2017. PMID: 28441579

9

Ligand-free Pd-catalyzed C-N cross-coupling/cyclization strategy: an unprecedented access to 1-thienyl pyrroloquinoxalines for the new approach towards apoptosis.

Kolli SK, Nakhi A, Archana S, Saridena M, Deora GS, Yellanki S, Medisetti R, Kulkarni P, Ramesh Raju R, Pal M. Kolli SK, et al. Among authors: deora gs. Eur J Med Chem. 2014 Oct 30;86:270-8. doi: 10.1016/j.ejmech.2014.08.057. Epub 2014 Aug 17. Eur J Med Chem. 2014. PMID: 25171781

10

Synthesis of 2,2,4-trimethyl-1,2-dihydroquinolinyl substituted 1,2,3-triazole derivatives: their evaluation as potential PDE 4B inhibitors possessing cytotoxic properties against cancer cells.

Praveena KS, Durgadas S, Suresh Babu N, Akkenapally S, Ganesh Kumar C, Deora GS, Murthy NY, Mukkanti K, Pal S. Praveena KS, et al. Among authors: deora gs. Bioorg Chem. 2014 Apr;53:8-14. doi: 10.1016/j.bioorg.2013.12.002. Epub 2013 Dec 30. Bioorg Chem. 2014. PMID: 24463218

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