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Protein kinase CK2 governs the molecular decision between encephalitogenic TH17 cell and Treg cell development.
Ulges A, Witsch EJ, Pramanik G, Klein M, Birkner K, Bühler U, Wasser B, Luessi F, Stergiou N, Dietzen S, Brühl TJ, Bohn T, Bündgen G, Kunz H, Waisman A, Schild H, Schmitt E, Zipp F, Bopp T. Ulges A, et al. Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):10145-50. doi: 10.1073/pnas.1523869113. Epub 2016 Aug 23. Proc Natl Acad Sci U S A. 2016. PMID: 27555590 Free PMC article.
Interferon-regulatory factor 4 is essential for the developmental program of T helper 9 cells.
Staudt V, Bothur E, Klein M, Lingnau K, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Ulges A, Taube C, Dehzad N, Becker M, Stassen M, Steinborn A, Lohoff M, Schild H, Schmitt E, Bopp T. Staudt V, et al. Among authors: ulges a. Immunity. 2010 Aug 27;33(2):192-202. doi: 10.1016/j.immuni.2010.07.014. Epub 2010 Jul 30. Immunity. 2010. PMID: 20674401 Free article.
Targeting prohibitins at the cell surface prevents Th17-mediated autoimmunity.
Buehler U, Schulenburg K, Yurugi H, Šolman M, Abankwa D, Ulges A, Tenzer S, Bopp T, Thiede B, Zipp F, Rajalingam K. Buehler U, et al. Among authors: ulges a. EMBO J. 2018 Aug 15;37(16):e99429. doi: 10.15252/embj.201899429. Epub 2018 Jul 26. EMBO J. 2018. PMID: 30049713 Free PMC article.
Tick Salivary Sialostatin L Represses the Initiation of Immune Responses by Targeting IRF4-Dependent Transcription in Murine Mast Cells.
Klein M, Brühl TJ, Staudt V, Reuter S, Grebe N, Gerlitzki B, Hoffmann M, Bohn T, Ulges A, Stergiou N, de Graaf J, Löwer M, Taube C, Becker M, Hain T, Dietzen S, Stassen M, Huber M, Lohoff M, Campos Chagas A, Andersen J, Kotál J, Langhansová H, Kopecký J, Schild H, Kotsyfakis M, Schmitt E, Bopp T. Klein M, et al. Among authors: ulges a. J Immunol. 2015 Jul 15;195(2):621-31. doi: 10.4049/jimmunol.1401823. Epub 2015 Jun 15. J Immunol. 2015. PMID: 26078269 Free PMC article.
Protein kinase CK2 enables regulatory T cells to suppress excessive TH2 responses in vivo.
Ulges A, Klein M, Reuter S, Gerlitzki B, Hoffmann M, Grebe N, Staudt V, Stergiou N, Bohn T, Brühl TJ, Muth S, Yurugi H, Rajalingam K, Bellinghausen I, Tuettenberg A, Hahn S, Reißig S, Haben I, Zipp F, Waisman A, Probst HC, Beilhack A, Buchou T, Filhol-Cochet O, Boldyreff B, Breloer M, Jonuleit H, Schild H, Schmitt E, Bopp T. Ulges A, et al. Nat Immunol. 2015 Mar;16(3):267-75. doi: 10.1038/ni.3083. Epub 2015 Jan 19. Nat Immunol. 2015. PMID: 25599562
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