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Cardiac-specific ablation of ARNT leads to lipotoxicity and cardiomyopathy.
Wu R, Chang HC, Khechaduri A, Chawla K, Tran M, Chai X, Wagg C, Ghanefar M, Jiang X, Bayeva M, Gonzalez F, Lopaschuk G, Ardehali H. Wu R, et al. Among authors: khechaduri a. J Clin Invest. 2014 Nov;124(11):4795-806. doi: 10.1172/JCI76737. Epub 2014 Oct 20. J Clin Invest. 2014. PMID: 25329697 Free PMC article.
Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.
Sawicki KT, Shang M, Wu R, Chang HC, Khechaduri A, Sato T, Kamide C, Liu T, Naga Prasad SV, Ardehali H. Sawicki KT, et al. Among authors: khechaduri a. J Am Heart Assoc. 2015 Jul 31;4(8):e002272. doi: 10.1161/JAHA.115.002272. J Am Heart Assoc. 2015. PMID: 26231844 Free PMC article.
Heme levels are increased in human failing hearts.
Khechaduri A, Bayeva M, Chang HC, Ardehali H. Khechaduri A, et al. J Am Coll Cardiol. 2013 May 7;61(18):1884-93. doi: 10.1016/j.jacc.2013.02.012. Epub 2013 Mar 6. J Am Coll Cardiol. 2013. PMID: 23500306 Free PMC article.
ATP-binding cassette B10 regulates early steps of heme synthesis.
Bayeva M, Khechaduri A, Wu R, Burke MA, Wasserstrom JA, Singh N, Liesa M, Shirihai OS, Langer NB, Paw BH, Ardehali H. Bayeva M, et al. Among authors: khechaduri a. Circ Res. 2013 Jul 19;113(3):279-87. doi: 10.1161/CIRCRESAHA.113.301552. Epub 2013 May 29. Circ Res. 2013. PMID: 23720443 Free PMC article.
mTOR regulates cellular iron homeostasis through tristetraprolin.
Bayeva M, Khechaduri A, Puig S, Chang HC, Patial S, Blackshear PJ, Ardehali H. Bayeva M, et al. Among authors: khechaduri a. Cell Metab. 2012 Nov 7;16(5):645-57. doi: 10.1016/j.cmet.2012.10.001. Epub 2012 Oct 25. Cell Metab. 2012. PMID: 23102618 Free PMC article.
16 results