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TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC. Thornton P, et al. Among authors: gomez perez nievas b. EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673. EMBO Mol Med. 2017. PMID: 28855301 Free PMC article.
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer's disease.
Kerr F, Sofola-Adesakin O, Ivanov DK, Gatliff J, Gomez Perez-Nievas B, Bertrand HC, Martinez P, Callard R, Snoeren I, Cochemé HM, Adcott J, Khericha M, Castillo-Quan JI, Wells G, Noble W, Thornton J, Partridge L. Kerr F, et al. Among authors: gomez perez nievas b. PLoS Genet. 2017 Mar 2;13(3):e1006593. doi: 10.1371/journal.pgen.1006593. eCollection 2017 Mar. PLoS Genet. 2017. PMID: 28253260 Free PMC article.
(Lost) gut feeling.
Gomez Perez-Nievas B. Gomez Perez-Nievas B. Nat Neurosci. 2023 Jul;26(7):1139. doi: 10.1038/s41593-023-01383-8. Nat Neurosci. 2023. PMID: 37414953 No abstract available.
Lessons from resilience.
Gomez Perez-Nievas B. Gomez Perez-Nievas B. Nat Neurosci. 2023 Jun;26(6):923. doi: 10.1038/s41593-023-01362-z. Nat Neurosci. 2023. PMID: 37280401 No abstract available.