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TREM2 shedding by cleavage at the H157-S158 bond is accelerated for the Alzheimer's disease-associated H157Y variant.
Thornton P, Sevalle J, Deery MJ, Fraser G, Zhou Y, Ståhl S, Franssen EH, Dodd RB, Qamar S, Gomez Perez-Nievas B, Nicol LS, Eketjäll S, Revell J, Jones C, Billinton A, St George-Hyslop PH, Chessell I, Crowther DC. Thornton P, et al. Among authors: jones c. EMBO Mol Med. 2017 Oct;9(10):1366-1378. doi: 10.15252/emmm.201707673. EMBO Mol Med. 2017. PMID: 28855301 Free PMC article.
Antibodies binding the head domain of P2X4 inhibit channel function and reverse neuropathic pain.
Williams WA, Linley JE, Jones CA, Shibata Y, Snijder A, Button J, Hatcher JP, Huang L, Taddese B, Thornton P, Schofield DJ, Thom G, Popovic B, Dosanjh B, Wilkinson T, Hughes J, Dobson CL, Groves MA, Webster CI, Billinton A, Vaughan TJ, Chessell I. Williams WA, et al. Pain. 2019 Sep;160(9):1989-2003. doi: 10.1097/j.pain.0000000000001587. Pain. 2019. PMID: 31045747
Changes in the Oligodendrocyte Progenitor Cell Proteome with Ageing.
de la Fuente AG, Queiroz RML, Ghosh T, McMurran CE, Cubillos JF, Bergles DE, Fitzgerald DC, Jones CA, Lilley KS, Glover CP, Franklin RJM. de la Fuente AG, et al. Among authors: jones ca. Mol Cell Proteomics. 2020 Aug;19(8):1281-1302. doi: 10.1074/mcp.RA120.002102. Epub 2020 May 20. Mol Cell Proteomics. 2020. PMID: 32434922 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33451504
CNS Remyelination and the Innate Immune System.
McMurran CE, Jones CA, Fitzgerald DC, Franklin RJ. McMurran CE, et al. Among authors: jones ca. Front Cell Dev Biol. 2016 May 3;4:38. doi: 10.3389/fcell.2016.00038. eCollection 2016. Front Cell Dev Biol. 2016. PMID: 27200350 Free PMC article. Review.
IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis.
Lindahl H, Guerreiro-Cacais AO, Bedri SK, Linnerbauer M, Lindén M, Abdelmagid N, Tandre K, Hollins C, Irving L, Glover C, Jones C, Alfredsson L, Rönnblom L, Kockum I, Khademi M, Jagodic M, Olsson T. Lindahl H, et al. Among authors: jones c. J Immunol. 2019 Aug 15;203(4):888-898. doi: 10.4049/jimmunol.1900400. Epub 2019 Jul 10. J Immunol. 2019. PMID: 31292217
Targeting the GM-CSF receptor for the treatment of CNS autoimmunity.
Ifergan I, Davidson TS, Kebir H, Xu D, Palacios-Macapagal D, Cann J, Rodgers JM, Hunter ZN, Pittet CL, Beddow S, Jones CA, Prat A, Sleeman MA, Miller SD. Ifergan I, et al. J Autoimmun. 2017 Nov;84:1-11. doi: 10.1016/j.jaut.2017.06.005. Epub 2017 Jun 20. J Autoimmun. 2017. PMID: 28641926 Free PMC article.
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