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Page 1
Preclinical studies reveal that LSD1 inhibition results in tumor growth arrest in lung adenocarcinoma independently of driver mutations.
Macheleidt IF, Dalvi PS, Lim SY, Meemboor S, Meder L, Käsgen O, Müller M, Kleemann K, Wang L, Nürnberg P, Rüsseler V, Schäfer SC, Mahabir E, Büttner R, Odenthal M. Macheleidt IF, et al. Mol Oncol. 2018 Nov;12(11):1965-1979. doi: 10.1002/1878-0261.12382. Epub 2018 Oct 13. Mol Oncol. 2018. PMID: 30220105 Free PMC article.
LSD1 Inhibition Attenuates Tumor Growth by Disrupting PLK1 Mitotic Pathway.
Dalvi PS, Macheleidt IF, Lim SY, Meemboor S, Müller M, Eischeid-Scholz H, Schaefer SC, Buettner R, Klein S, Odenthal M. Dalvi PS, et al. Among authors: macheleidt if. Mol Cancer Res. 2019 Jun;17(6):1326-1337. doi: 10.1158/1541-7786.MCR-18-0971. Epub 2019 Feb 13. Mol Cancer Res. 2019. PMID: 30760542
Author Correction: LSD1 modulates the non-canonical integrin β3 signaling pathway in non-small cell lung carcinoma cells.
Lim SY, Macheleidt I, Dalvi P, Schäfer SC, Kerick M, Ozretić L, Ortiz-Cuaran S, George J, Merkelbach-Bruse S, Wolf J, Timmermann B, Thomas RK, Schweiger MR, Buettner R, Odenthal M. Lim SY, et al. Among authors: macheleidt i. Sci Rep. 2018 Nov 1;8(1):16452. doi: 10.1038/s41598-018-31451-0. Sci Rep. 2018. PMID: 30382114 Free PMC article.
LIN28B enhanced tumorigenesis in an autochthonous KRASG12V-driven lung carcinoma mouse model.
Meder L, König K, Dietlein F, Macheleidt I, Florin A, Ercanoglu MS, Rommerscheidt-Fuss U, Koker M, Schön G, Odenthal M, Klein F, Büttner R, Schulte JH, Heukamp LC, Ullrich RT. Meder L, et al. Among authors: macheleidt i. Oncogene. 2018 May;37(20):2746-2756. doi: 10.1038/s41388-018-0158-7. Epub 2018 Mar 5. Oncogene. 2018. PMID: 29503447
Novel functional role of GH/IGF-I in neonatal lung myofibroblasts and in rat lung growth after intrauterine growth restriction.
Nawabi J, Vohlen C, Dinger K, Thangaratnarajah C, Klaudt C, Lopez Garcia E, Hirani DV, Karakaya PH, Macheleidt I, Odenthal M, Nüsken KD, Dötsch J, Alejandre Alcazar MA. Nawabi J, et al. Among authors: macheleidt i. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L623-L637. doi: 10.1152/ajplung.00413.2017. Epub 2018 Jul 26. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30047284 Free article.
Inhibition of CPAP-tubulin interaction prevents proliferation of centrosome-amplified cancer cells.
Mariappan A, Soni K, Schorpp K, Zhao F, Minakar A, Zheng X, Mandad S, Macheleidt I, Ramani A, Kubelka T, Dawidowski M, Golfmann K, Wason A, Yang C, Simons J, Schmalz HG, Hyman AA, Aneja R, Ullrich R, Urlaub H, Odenthal M, Büttner R, Li H, Sattler M, Hadian K, Gopalakrishnan J. Mariappan A, et al. Among authors: macheleidt i. EMBO J. 2019 Jan 15;38(2):e99876. doi: 10.15252/embj.201899876. Epub 2018 Dec 10. EMBO J. 2019. PMID: 30530478 Free PMC article.
YB-1 increases glomerular, but decreases interstitial fibrosis in CNI-induced nephropathy.
Gibbert L, Hermert D, Wang J, M Breitkopf D, Alidousty C, Neusser M, Cohen CD, Gröne E, Macheleidt I, Rauen T, Braun GS, Floege J, Ostendorf T, Raffetseder U. Gibbert L, et al. Among authors: macheleidt i. Clin Immunol. 2018 Sep;194:67-74. doi: 10.1016/j.clim.2018.07.002. Epub 2018 Jul 3. Clin Immunol. 2018. PMID: 30018024