Chen J - Search Results

1

14-3-3ζ binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.

Gu Y, Xu K, Torre C, Samur M, Barwick BG, Rupji M, Arora J, Neri P, Kaufman J, Nooka A, Bernal-Mizrachi L, Vertino P, Sun SY, Chen J, Munshi N, Fu H, Kowalski J, Boise LH, Lonial S. Gu Y, et al. Among authors: chen j. Leukemia. 2018 Mar;32(3):744-751. doi: 10.1038/leu.2017.288. Epub 2017 Sep 19. Leukemia. 2018. PMID: 28924240

2

Suppression of apoptosis signal-regulating kinase 1-induced cell death by 14-3-3 proteins.

Zhang L, Chen J, Fu H. Zhang L, et al. Among authors: chen j. Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8511-5. doi: 10.1073/pnas.96.15.8511. Proc Natl Acad Sci U S A. 1999. PMID: 10411906 Free PMC article.

3

Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism.

Chen J, Fujii K, Zhang L, Roberts T, Fu H. Chen J, et al. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7783-8. doi: 10.1073/pnas.141224398. Epub 2001 Jun 26. Proc Natl Acad Sci U S A. 2001. PMID: 11427728 Free PMC article.

4

MicroRNA-21 functions as an oncogene and promotes cell proliferation and invasion via TIMP3 in renal cancer.

Chen J, Gu Y, Shen W. Chen J, et al. Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4566-4576. Eur Rev Med Pharmacol Sci. 2017. PMID: 29131259 Free article.

5

Targeting phospho-MARCKS overcomes drug-resistance and induces antitumor activity in preclinical models of multiple myeloma.

Yang Y, Chen Y, Saha MN, Chen J, Evans K, Qiu L, Reece D, Chen GA, Chang H. Yang Y, et al. Among authors: chen j, chen ga, chen y. Leukemia. 2015 Mar;29(3):715-26. doi: 10.1038/leu.2014.255. Epub 2014 Sep 2. Leukemia. 2015. PMID: 25179733

6

Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin.

Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, Lonial S, Gaddh M, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, Fan J, Chen J. Elf S, et al. Among authors: chen j. Oncogene. 2017 Jan 12;36(2):254-262. doi: 10.1038/onc.2016.196. Epub 2016 Jun 6. Oncogene. 2017. PMID: 27270429 Free PMC article.

7

Sensitizing acute myeloid leukemia cells to induced differentiation by inhibiting the RIP1/RIP3 pathway.

Xin J, You D, Breslin P, Li J, Zhang J, Wei W, Cannova J, Volk A, Gutierrez R, Xiao Y, Ni A, Ng G, Schmidt R, Xia Z, Pan J, Chen H, Patel MM, Kuo PC, Nand S, Kini AR, Zhang J, Chen J, Zhu J, Zhang J. Xin J, et al. Among authors: chen j, chen h. Leukemia. 2017 May;31(5):1154-1165. doi: 10.1038/leu.2016.287. Epub 2016 Oct 17. Leukemia. 2017. PMID: 27748372 Free PMC article.

8

[Comparison of single infusion of anti-BCMA versus combined infusion of anti-CD19 chimeric antigen receptor T cells for immune reconstruction in relapsed/refractory multiple myeloma].

Ge J, Zhao TT, Wan CY, Xia JY, Guo SY, Yu MX, Chen J, Wang Y, Xu KL, Li ZY. Ge J, et al. Among authors: chen j. Zhonghua Xue Ye Xue Za Zhi. 2021 Sep 14;42(9):733-738. doi: 10.3760/cma.j.issn.0253-2727.2021.09.004. Zhonghua Xue Ye Xue Za Zhi. 2021. PMID: 34753227 Free PMC article. Chinese.

9

The WHIM-like CXCR4(S338X) somatic mutation activates AKT and ERK, and promotes resistance to ibrutinib and other agents used in the treatment of Waldenstrom's Macroglobulinemia.

Cao Y, Hunter ZR, Liu X, Xu L, Yang G, Chen J, Patterson CJ, Tsakmaklis N, Kanan S, Rodig S, Castillo JJ, Treon SP. Cao Y, et al. Among authors: chen j. Leukemia. 2015 Jan;29(1):169-76. doi: 10.1038/leu.2014.187. Epub 2014 Jun 10. Leukemia. 2015. PMID: 24912431

10

Regulation of PI3K signaling in T-cell acute lymphoblastic leukemia: a novel PTEN/Ikaros/miR-26b mechanism reveals a critical targetable role for PIK3CD.

Yuan T, Yang Y, Chen J, Li W, Li W, Zhang Q, Mi Y, Goswami RS, You JQ, Lin D, Qian MD, Calin S, Liang Y, Miranda RN, Calin GA, Zhou X, Ma L, Zweidler-McKay PA, Liu B, Weng AP, Medeiros LJ, Zhang Y, You MJ. Yuan T, et al. Among authors: chen j. Leukemia. 2017 Nov;31(11):2355-2364. doi: 10.1038/leu.2017.80. Epub 2017 Mar 10. Leukemia. 2017. PMID: 28280276 Free PMC article.

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